Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDK1 | Q15118 | 1/20 | 0.40 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.40 |
| ▸ | PDK3 | Q15120 | 1/20 | 0.40 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.40 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.37 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.36 |
| ▸ | MEN1 | O00255 | 3/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 3/20 | 0.35 |
| ▸ | RGS12 | O14924 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | F10 | P00742 | 2/20 | 0.35 |
| ▸ | F2 | P00734 | 2/20 | 0.35 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6979019 | 0.74 | ITGB3 (0.39) | ITGB3ITGA2BGAATSHRHTT | |
| SCHEMBL6982396 | 0.74 | ITGB3 (0.35) | ITGB3ITGA2BGAATSHRALDH1A1 | |
| SCHEMBL9558850 | 0.68 | ITGB3 (0.53) | ITGB3ITGA2BF10F2PRSS1 | |
| SCHEMBL9263893 | 0.68 | KLK1 (0.38) | ITGB3ITGA2BF2PRSS1PRSS2 | |
| SCHEMBL4414766 | 0.64 | F7 (0.57) | ITGB3ITGA2BF10F2PRSS1 | |
| SCHEMBL7348941 | 0.64 | ITGB3 (0.57) | ITGB3ITGA2BGAAMAPT | |
| SCHEMBL7347870 | 0.64 | ITGB3 (0.57) | ITGB3ITGA2BGAAHTTMAPT | |
| SCHEMBL6981952 | 0.63 | ALDH1A1 (0.49) | ITGB3ITGA2BKMT2AHTTMAPT | |
| SCHEMBL6978796 | 0.62 | ITGB3 (0.48) | ITGB3ITGA2BGAATSHRPOLB | |
| SCHEMBL1542395 | 0.62 | PDK1 (0.74) | PDK1PDK2PDK3PDK4GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5378727-A | ADMINISTERING TO MAMMALS | G. D. SEARLE & CO. (US) | 1995-01-03 | — | — | US | disclosed |
| US-5254573-A | Substituted heterocyclic derivatives useful as platelet aggregation inhibitors | MONSANTO COMPANY (US) | 1993-10-19 | — | — | US | disclosed |
| EP-0539343-A1 | Substituted heterocyclic derivatives useful as platelet aggregation inhibitors | MONSANTO COMPANY (US) | 1993-04-28 | — | — | EP | disclosed |