Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.50 |
| ▸ | MAPT | P10636 | 4/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 3/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.42 |
| ▸ | APP | P05067 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Alcohol SCHEMBL11561027 | 0.92 | ALDH1A1 (0.44) | ALDH1A1KDM4EMAPTKMT2APTGS2 | |
| SCHEMBL28182115 | 0.83 | MAPT (0.43) | ALDH1A1KDM4EMAPTKMT2AHPGD | |
| SCHEMBL16300950 | 0.81 | ALOX5 (0.49) | ALDH1A1KDM4EMAPTKMT2APTGS2 | |
| SCHEMBL31609684 | 0.80 | KMT2A (0.45) | ALDH1A1KDM4EMAPTKMT2APTGS2 | |
| SCHEMBL9256402 | 0.80 | KMT2A (0.45) | ALDH1A1KDM4EMAPTKMT2APTGS2 | |
| SCHEMBL2088457 | 0.77 | PTGS2 (0.42) | ALDH1A1KDM4EMAPTKMT2APTGS2 | |
| SCHEMBL5815370 | 0.76 | POLB (0.40) | ALDH1A1KDM4EMAPTKMT2AHPGD | |
| SCHEMBL2088458 | 0.76 | PTGS2 (0.41) | ALDH1A1KDM4EMAPTPTGS2LMNA | |
| SCHEMBL5813457 | 0.74 | NPC1 (0.39) | ALDH1A1KDM4EMAPTKMT2AHPGD | |
| SCHEMBL926914 | 0.74 | KDM4E (0.55) | ALDH1A1KDM4EMAPTGAAADORA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 103 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4168315-A | ANTICOAGULANTS | THE UPJOHN COMPANY (US) | 1979-09-18 | — | — | US | claimed |
| EP-2006738-B1 | Lithographic printing plate precursor | FUJIFILM CORP (JP) | 2017-09-06 | — | — | EP | disclosed |
| EP-2259141-B1 | PROCESS FOR PRODUCING LITHOGRAPHIC PRINTING PLATE | FUJIFILM CORP (JP) | 2016-11-23 | — | — | EP | disclosed |
| EP-1939687-B1 | Polymerizable composition and lithographic printing plate precursor | FUJIFILM CORP (JP) | 2016-09-14 | — | — | EP | disclosed |
| EP-2503393-B2 | Method for preparation of lithographic printing plate | FUJIFILM CORP (JP) | 2016-07-20 | — | — | EP | disclosed |
| EP-2042312-B1 | Processing method of lithographic printing plate precursor | FUJIFILM CORP (JP) | 2016-05-18 | — | — | EP | disclosed |
| EP-3021167-A1 | LITHOGRAPHIC PRINTING PLATE PRECURSOR AND METHOD OF PREPARING LITHOGRAPHIC PRINTING PLATE | Fujifilm Corporation (JP) | 2016-05-18 | — | — | EP | disclosed |
| EP-2045662-B1 | Lithographic printing plate precursor and method of preparing lithographic printing plate | FUJIFILM CORP (JP) | 2015-12-23 | — | — | EP | disclosed |
| EP-1975708-B1 | Lithographic printing plate precursor | FUJIFILM CORP (JP) | 2015-04-22 | — | — | EP | disclosed |
| EP-2662729-B1 | Method for preparation of lithographic printing plate | FUJIFILM CORP (JP) | 2014-10-22 | — | — | EP | disclosed |
| EP-0772606-A1 | SUBSTITUTED THIAZOLES FOR THE TREATMENT OF INFLAMMATION | G.D. SEARLE & CO. (US) | 1997-05-14 | — | — | EP | disclosed |
| WO-1996003392-A1 | SUBSTITUTED THIAZOLES FOR THE TREATMENT OF INFLAMMATION | G.D. SEARLE & CO. (US) | 1996-02-08 | — | — | WO | disclosed |
| EP-0159677-B1 | NOVEL 4,5-BIS(4-METHOXYPHENYL)-2-(PYRROL-2-YL)THIAZOLES, PROCESS FOR THE PREPARATION THEREOF AND PHARMACEUTICAL COMPOSITION CONTAINING THE SAME | KANEBO, LTD. (JP) | 1989-02-22 | — | — | EP | disclosed |
| US-4659726-A | ANTICOAGULANTS | KANEBO, LTD. (JP) | 1987-04-21 | — | — | US | disclosed |
| EP-0159677-A2 | Novel 4,5-bis(4-methoxyphenyl)-2-(pyrrol-2-yl)thiazoles, process for the preparation thereof and pharmaceutical composition containing the same | KANEBO, LTD. (JP) | 1985-10-30 | — | — | EP | disclosed |
| US-4451471-A | Certain 2,4,5-tri-substituted thiazoles, pharmaceutical compositions containing same and methods of using same | CIBA-GEIGY CORPORATION (US) | 1984-05-29 | — | — | US | disclosed |
| EP-0061425-A2 | Thiazole derivatives, processes for their preparation, medicaments containing them and their use | CIBA-GEIGY AG (CH) | 1982-09-29 | — | — | EP | disclosed |
| US-4322428-A | 2(4-Fluorophenyl)-4,5,-bis(4-methoxyphenyl)thiazole and method of use | ELI LILLY AND COMPANY (US) | 1982-03-30 | — | — | US | disclosed |
| EP-0037274-A1 | Substituted triaryl thiazole compounds | ELI LILLY AND COMPANY (US) | 1981-10-07 | — | — | EP | disclosed |
| US-4168315-A | ANTICOAGULANTS | THE UPJOHN COMPANY (US) | 1979-09-18 | — | — | US | disclosed |