Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | CASP1 | P29466 | 1/20 | 0.40 |
| ▸ | CASP7 | P55210 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | GFER | P55789 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | CHRNB2 | P17787 | 2/20 | 0.38 |
| ▸ | CHRNA7 | P36544 | 2/20 | 0.38 |
| ▸ | CHRNA4 | P43681 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | HTR6 | P50406 | 1/20 | 0.37 |
| ▸ | CNR1 | P21554 | 4/20 | 0.37 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.37 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.36 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9271449 | 0.80 | MAPT (0.57) | ALDH1A1KDM4EMAPTGAACASP1 | |
| SCHEMBL9266502 | 0.73 | MAP2 (0.50) | ALDH1A1KDM4EMAPTGAACASP1 | |
| SCHEMBL18642000 | 0.72 | MAPT (0.49) | ALDH1A1KDM4EMAPTGAACASP1 | |
| SCHEMBL9017539 | 0.71 | AHR (0.59) | ALDH1A1GAAGFERHTTCNR1 | |
| SCHEMBL9017534 | 0.69 | PTGS2 (0.43) | ALDH1A1KDM4EGAAGFERHTT | |
| SCHEMBL8307123 | 0.68 | PTGS2 (0.45) | ALDH1A1KDM4EMAPTGAAHTT | |
| SCHEMBL14028854 | 0.68 | KDM4E (0.44) | ALDH1A1KDM4EMAPTGAACASP1 | |
| SCHEMBL10819611 | 0.66 | MAPT (0.61) | ALDH1A1KDM4EMAPTGAACASP1 | |
| SCHEMBL4238498 | 0.63 | CNR1 (0.52) | ALDH1A1MAPTGAAGFERCNR1 | |
| SCHEMBL9664534 | 0.62 | MAPT (0.65) | ALDH1A1KDM4EMAPTGAACASP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5436264-A | Adrenergic blocking agents for vasoconstriction and hypotensive agents | SYNTEX (U.S.A.) INC. (US) | 1995-07-25 | — | — | US | disclosed |