Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC2A1 | P11166 | 1/20 | 0.50 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.39 |
| ▸ | SRD5A1 | P18405 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | USP2 | O75604 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.37 |
| ▸ | DRD2 | P14416 | 3/20 | 0.37 |
| ▸ | MAP1LC3B | Q9GZQ8 | 1/20 | 0.35 |
| ▸ | HTR3A | P46098 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9260967 | 1.00 | SLC2A1 (0.50) | SLC2A1PTGS2SRD5A1LMNAMEN1 | |
| SCHEMBL9261585 | 0.77 | PTGS2 (0.55) | PTGS2ALDH1A1NPC1RAB9A | |
| SCHEMBL9262871 | 0.75 | PTGS2 (0.39) | PTGS2MAPTNPC1RAB9A | |
| SCHEMBL9262860 | 0.75 | PTGS2 (0.39) | PTGS2MAPTNPC1RAB9A | |
| SCHEMBL9263690 | 0.74 | SLC2A1 (0.64) | SLC2A1SRD5A1LMNAMEN1USP2 | |
| SCHEMBL9263698 | 0.74 | SLC2A1 (0.64) | SLC2A1SRD5A1LMNAMEN1USP2 | |
| SCHEMBL9270193 | 0.73 | SLC2A1 (0.49) | SLC2A1SRD5A1LMNAMEN1USP2 | |
| SCHEMBL315186 | 0.70 | HTR3A (0.58) | SLC2A1SRD5A1LMNAMEN1USP2 | |
| Methyl Alcohol SCHEMBL15391253 | 0.68 | DRD2 (0.55) | SLC2A1SRD5A1LMNAMEN1USP2 | |
| SCHEMBL9263874 | 0.67 | PTGS2 (0.58) | PTGS2ALDH1A1NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5403934-A | Heterocyclic compounds | BURROUGHS WELLCOME CO. (US) | 1995-04-04 | — | — | US | disclosed |
| WO-1991013873-A1 | HETEROCYCLIC COMPOUNDS | THE WELLCOME FOUNDATION LIMITED (GB) | 1991-09-19 | — | — | WO | disclosed |
| EP-0447164-A1 | Heterocyclic compounds | THE WELLCOME FOUNDATION LIMITED (GB) | 1991-09-18 | — | — | EP | disclosed |