Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 2/20 | 0.42 |
| ▸ | OPRL1 | P41146 | 2/20 | 0.42 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | MAOA | P21397 | 1/20 | 0.36 |
| ▸ | MAOB | P27338 | 1/20 | 0.36 |
| ▸ | PYCR1 | P32322 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | BLM | P54132 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.35 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.35 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.34 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.34 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.34 |
| ▸ | PRMT8 | Q9NR22 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9260981 | 1.00 | OPRM1 (0.42) | OPRM1OPRL1SIGMAR1ALDH1A1TSHR | |
| SCHEMBL20741223 | 0.82 | ADRA2A (0.36) | OPRM1OPRL1SIGMAR1ALDH1A1TSHR | |
| SCHEMBL3241413 | 0.81 | OPRM1 (0.50) | OPRM1OPRL1ALDH1A1TSHRLMNA | |
| SCHEMBL27875481 | 0.79 | OPRM1 (0.49) | OPRM1OPRL1ALDH1A1TSHRLMNA | |
| SCHEMBL24738201 | 0.75 | OPRM1 (0.44) | OPRM1OPRL1ALDH1A1TSHRLMNA | |
| SCHEMBL13600125 | 0.74 | OPRM1 (0.43) | OPRM1OPRL1ALDH1A1TSHRLMNA | |
| SCHEMBL5674633 | 0.73 | OPRM1 (0.57) | OPRM1OPRL1SIGMAR1ALDH1A1TSHR | |
| SCHEMBL9180892 | 0.73 | OPRM1 (0.43) | OPRM1OPRL1SIGMAR1ALDH1A1TSHR | |
| SCHEMBL20741224 | 0.73 | ALDH1A1 (0.36) | OPRM1OPRL1SIGMAR1ALDH1A1TSHR | |
| SCHEMBL4446952 | 0.69 | CTSS (0.41) | OPRM1OPRL1ALDH1A1NAAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5436261-A | Adrenergic agonists | ADIR ET COMPAGNIE (FR) | 1995-07-25 | — | — | US | disclosed |