Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHUK | O15111 | 1/20 | 0.46 |
| ▸ | TXNRD1 | Q16881 | 1/20 | 0.46 |
| ▸ | NOX4 | Q9NPH5 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.43 |
| ▸ | ADORA2B | P29275 | 5/20 | 0.42 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.42 |
| ▸ | SPHK2 | Q9NRA0 | 1/20 | 0.42 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.42 |
| ▸ | S1PR1 | P21453 | 2/20 | 0.41 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.41 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.41 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4415503 | 0.74 | CHRM5 (0.65) | CHRM5ADRA1DADRA1AADRA1B | |
| SCHEMBL9272000 | 0.74 | LMNA (0.55) | CHUKTXNRD1NOX4MAPTSMN1; SMN2 | |
| SCHEMBL18935909 | 0.74 | MEN1 (0.42) | POLBMAPTSMN1; SMN2THRBCHRM5 | |
| SCHEMBL10081939 | 0.73 | LMNA (0.57) | CHUKTXNRD1NOX4MAPTSMN1; SMN2 | |
| SCHEMBL282099 | 0.73 | LMNA (0.54) | CHUKTXNRD1NOX4MAPTSMN1; SMN2 | |
| SCHEMBL2357444 | 0.73 | AR (0.40) | LMNATHRBADORA2BADORA3SPHK2 | |
| SCHEMBL13463603 | 0.72 | KCNH2 (0.59) | CHUKTXNRD1NOX4POLBSMN1; SMN2 | |
| SCHEMBL13064231 | 0.71 | ALDH1A1 (0.66) | MAPTSMN1; SMN2LMNATHRBADORA2B | |
| SCHEMBL13020876 | 0.71 | LMNA (0.55) | CHUKTXNRD1NOX4POLBMAPT | |
| SCHEMBL29892798 | 0.71 | TOP1 (0.47) | POLBCHRM5ADRA1DADRA1AADRA1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1995007278-A1 | FUNGICIDAL, MITICIDAL AND ARTHROPODICIDAL AMINOPYRIMIDINES | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1995-03-16 | — | — | WO | disclosed |