Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.55 |
| ▸ | THRB | P10828 | 1/20 | 0.55 |
| ▸ | S1PR1 | P21453 | 6/20 | 0.52 |
| ▸ | SPHK2 | Q9NRA0 | 2/20 | 0.48 |
| ▸ | CASP3 | P42574 | 3/20 | 0.47 |
| ▸ | S1PR3 | Q99500 | 2/20 | 0.46 |
| ▸ | NOTUM | Q6P988 | 2/20 | 0.45 |
| ▸ | CHUK | O15111 | 1/20 | 0.44 |
| ▸ | TXNRD1 | Q16881 | 1/20 | 0.44 |
| ▸ | NOX4 | Q9NPH5 | 1/20 | 0.44 |
| ▸ | PPARG | P37231 | 1/20 | 0.44 |
| ▸ | PPARD | Q03181 | 1/20 | 0.44 |
| ▸ | PPARA | Q07869 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL282099 | 0.85 | LMNA (0.54) | LMNATHRBS1PR1SPHK2CASP3 | |
| SCHEMBL10081939 | 0.85 | LMNA (0.57) | LMNATHRBS1PR1SPHK2CASP3 | |
| SCHEMBL13020876 | 0.83 | LMNA (0.55) | LMNATHRBS1PR1SPHK2CASP3 | |
| SCHEMBL13064231 | 0.83 | ALDH1A1 (0.66) | LMNATHRBS1PR1SPHK2CASP3 | |
| SCHEMBL30646380 | 0.79 | L3MBTL1 (0.39) | LMNATHRBS1PR1SPHK2CASP3 | |
| SCHEMBL19810876 | 0.77 | NOTUM (0.72) | LMNACASP3NOTUMNPC1MAPT | |
| SCHEMBL30646382 | 0.77 | MPL (0.46) | S1PR1CHUKTXNRD1NOX4NPC1 | |
| SCHEMBL30646388 | 0.77 | PLAT (0.38) | LMNATHRBS1PR1S1PR3CHUK | |
| SCHEMBL21776935 | 0.77 | NOTUM (0.70) | LMNANOTUMNPC1MAPTHPGD | |
| SCHEMBL30646377 | 0.76 | L3MBTL1 (0.43) | S1PR1CASP3S1PR3CHUKTXNRD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1995007278-A1 | FUNGICIDAL, MITICIDAL AND ARTHROPODICIDAL AMINOPYRIMIDINES | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1995-03-16 | — | — | WO | disclosed |