SCHEMBL9262018

SCHEMBL9262018

Cc1cc(O)nn1C(=O)O

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.40
ALDH1A1 P00352 4/20 0.39
MEN1 O00255 2/20 0.39
KMT2A Q03164 2/20 0.39
CYP1A2 P05177 1/20 0.39
CYP3A4 P08684 1/20 0.39
CYP2C9 P11712 1/20 0.39
CYP2C19 P33261 1/20 0.39
MAPK1 P28482 1/20 0.39
L3MBTL1 Q9Y468 1/20 0.39
POLB P06746 1/20 0.39
LMNA P02545 1/20 0.37
ENPP3 O14638 5/20 0.37
ALPL P05186 5/20 0.37
XIAP P98170 5/20 0.37
KDM4E B2RXH2 1/20 0.37
TP53 P04637 1/20 0.36
MAPT P10636 1/20 0.36
ALOX15 P16050 1/20 0.36
F12 P00748 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4457538 0.80 TSHR (0.60) TSHRALDH1A1MEN1KMT2ACYP1A2
Hydrochloric Acid SCHEMBL11561048 0.78 TSHR (0.58) TSHRALDH1A1MEN1KMT2ACYP1A2
SCHEMBL173908 0.77 ENPP3 (0.42) TSHRALDH1A1MEN1KMT2ACYP1A2
SCHEMBL28485155 0.77 ALDH1A1 (0.42) TSHRALDH1A1MEN1KMT2ACYP1A2
SCHEMBL16347339 0.74 TSHR (0.37) TSHRALDH1A1MEN1KMT2ACYP1A2
SCHEMBL19469174 0.70 MAPT (0.43) TSHRALDH1A1MEN1KMT2ACYP1A2
SCHEMBL1531077 0.69 KMT2A (0.38) TSHRALDH1A1MEN1KMT2ACYP1A2
SCHEMBL3399530 0.67 PTGS2 (0.49) ALDH1A1MEN1KMT2AL3MBTL1LMNA
SCHEMBL3393181 0.65 KDM4E (0.53) ALDH1A1MEN1KMT2ACYP1A2CYP2C19
Hydrochloric Acid SCHEMBL21981571 0.65

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5463031-A Printing, dyeing cellulose and organonitrogen compounds BAYER AKTIENGESELLSCHAFT (DE) 1995-10-31 US disclosed