Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 3/20 | 0.48 |
| ▸ | RAB9A | P51151 | 3/20 | 0.48 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.46 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.45 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.43 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 4/20 | 0.43 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.43 |
| ▸ | EPRS1 | P07814 | 1/20 | 0.41 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.41 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.41 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21198256 | 0.80 | MAPT (0.44) | PTGS2NPC1RAB9ARXFP1NR1H2 | |
| SCHEMBL3400232 | 0.80 | PHGDH (0.43) | MAPTMEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL13425885 | 0.80 | PTGS2 (0.43) | PTGS2NPC1RAB9APDE4BRXFP1 | |
| SCHEMBL3393979 | 0.79 | PDE4B (0.50) | NPC1RAB9APDE4BMAPTMEN1 | |
| SCHEMBL3395570 | 0.77 | MAPT (0.47) | MAPTKDM4EGAAL3MBTL1 | |
| SCHEMBL3395650 | 0.75 | KMO (0.49) | MAPTALDH1A1 | |
| SCHEMBL3399098 | 0.74 | PDE4B (0.49) | PDE4BKDM4EGAA | |
| SCHEMBL3398387 | 0.74 | PTGS2 (0.53) | PTGS2NPC1RAB9APDE4BMAPT | |
| SCHEMBL4692583 | 0.71 | PTPN1 (0.52) | RXFP1MAPTMEN1KMT2AMCL1 | |
| SCHEMBL4898612 | 0.70 | NPC1 (0.47) | PTGS2NPC1RAB9ARXFP1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010046780-A2 | ANTI VIRAL COMPOUNDS | INSTITUT PASTEUR KOREA (KR) | 2010-04-29 | — | — | WO | disclosed |