Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 5/20 | 0.50 |
| ▸ | SIRT1 | Q96EB6 | 3/20 | 0.50 |
| ▸ | HTR7 | P34969 | 3/20 | 0.50 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.50 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.50 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.50 |
| ▸ | HTR2B | P41595 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | MAP3K14 | Q99558 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | HTR3A | P46098 | 2/20 | 0.40 |
| ▸ | IDO1 | P14902 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | HTR1B | P28222 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9267967 | 0.79 | HTR1D (0.62) | HTR6HTR7HTR2BCYP1A2HPGD | |
| SCHEMBL4241023 | 0.78 | AHR (0.48) | HTR6LMNACYP1A2GAAHPGD | |
| SCHEMBL28750432 | 0.75 | HTR6 (0.68) | HTR6SIRT1HTR7ADRA2AADRA2B | |
| SCHEMBL18370061 | 0.74 | HTR6 (0.63) | HTR6SIRT1HTR7ADRA2AADRA2B | |
| SCHEMBL23657217 | 0.74 | HTR6 (0.67) | HTR6SIRT1HTR7ADRA2AADRA2B | |
| Hydrochloric Acid SCHEMBL892350 | 0.74 | HTR6 (0.67) | HTR6SIRT1HTR7ADRA2AADRA2B | |
| SCHEMBL9257404 | 0.73 | HTR6 (0.57) | HTR6SIRT1HTR7ADRA2AADRA2B | |
| Hydrochloric Acid SCHEMBL23649325 | 0.73 | HTR6 (0.65) | HTR6SIRT1HTR7ADRA2AADRA2B | |
| SCHEMBL3632803 | 0.72 | LMNA (0.53) | HTR6SIRT1HTR7ADRA2AADRA2B | |
| Cyanide SCHEMBL28561199 | 0.72 | HTR6 (0.63) | HTR6SIRT1HTR7ADRA2AADRA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5436264-A | Adrenergic blocking agents for vasoconstriction and hypotensive agents | SYNTEX (U.S.A.) INC. (US) | 1995-07-25 | — | — | US | disclosed |