Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1D | P28221 | 3/20 | 0.62 |
| ▸ | HTR6 | P50406 | 3/20 | 0.62 |
| ▸ | HTR1A | P08908 | 2/20 | 0.52 |
| ▸ | HTR7 | P34969 | 2/20 | 0.52 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.52 |
| ▸ | HTR1E | P28566 | 1/20 | 0.52 |
| ▸ | HTR5A | P47898 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.51 |
| ▸ | MAPT | P10636 | 6/20 | 0.51 |
| ▸ | MEN1 | O00255 | 5/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.51 |
| ▸ | GFER | P55789 | 2/20 | 0.51 |
| ▸ | TSHR | P16473 | 2/20 | 0.51 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.50 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.50 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.49 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.47 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11488805 | 0.84 | HTR6 (0.58) | HTR1DHTR6HTR1AHTR7SLC6A2 | |
| SCHEMBL9262224 | 0.79 | HTR6 (0.50) | HTR1DHTR6HTR7ALDH1A1MAPT | |
| SCHEMBL4244966 | 0.77 | HTR1D (1.00) | HTR1DHTR6HTR1AHTR7SLC6A2 | |
| SCHEMBL5116957 | 0.76 | AKR1C2 (0.58) | HTR1DHTR6HTR1AHTR7SLC6A2 | |
| Hydrochloric Acid SCHEMBL7433474 | 0.75 | HTR1D (0.97) | HTR1DHTR6HTR1AHTR7SLC6A2 | |
| SCHEMBL4241023 | 0.75 | AHR (0.48) | HTR6ALDH1A1KDM4EMAPTMEN1 | |
| SCHEMBL9263297 | 0.74 | HTR6 (0.66) | HTR1DHTR6HTR1AHTR7SLC6A2 | |
| SCHEMBL8578417 | 0.74 | AKR1C2 (0.55) | HTR1DHTR6HTR1AHTR7SLC6A2 | |
| Cyanide SCHEMBL28561862 | 0.73 | HTR1D (0.92) | HTR1DHTR6HTR1AHTR7SLC6A2 | |
| SCHEMBL7806663 | 0.73 | HTR1D (0.82) | HTR1DHTR6HTR1AHTR7SLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5436264-A | Adrenergic blocking agents for vasoconstriction and hypotensive agents | SYNTEX (U.S.A.) INC. (US) | 1995-07-25 | — | — | US | disclosed |