Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AHR | P35869 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 5/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | HTT | P42858 | 2/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | HTR6 | P50406 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | CASP1 | P29466 | 1/20 | 0.41 |
| ▸ | CASP7 | P55210 | 1/20 | 0.41 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24367843 | 0.84 | AHR (0.50) | AHRMAPTCYP3A4ALDH1A1HTT | |
| SCHEMBL14214508 | 0.80 | AHR (0.57) | AHRMAPTCYP3A4ALDH1A1HTT | |
| SCHEMBL9262224 | 0.78 | HTR6 (0.50) | MAPTCYP3A4ALDH1A1CYP1A2CYP2C9 | |
| SCHEMBL9267967 | 0.75 | HTR1D (0.62) | MAPTALDH1A1HTTTSHRCYP1A2 | |
| SCHEMBL24611517 | 0.74 | AHR (0.55) | AHRMAPTCYP3A4ALDH1A1HTT | |
| SCHEMBL7809398 | 0.74 | MAPT (0.50) | AHRMAPTCYP3A4ALDH1A1HTT | |
| SCHEMBL19059390 | 0.72 | AHR (0.44) | AHRMAPTCYP3A4ALDH1A1HTT | |
| SCHEMBL7915043 | 0.71 | AHR (0.52) | AHRMAPTCYP3A4ALDH1A1HTT | |
| SCHEMBL11039347 | 0.71 | BRD4 (0.34) | MAPTALDH1A1HTTCYP1A2CYP2C9 | |
| SCHEMBL9664534 | 0.71 | MAPT (0.65) | AHRMAPTCYP3A4ALDH1A1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009034464-A2 | INDOLE RELATED COMPOUNDS WITH PHYSIOLOGICAL ACTIVITY | NEWCASTLE INNOVATION LIMITED (AU) | 2009-03-19 | — | — | WO | disclosed |