Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR4A2 | P43354 | 3/20 | 0.45 |
| ▸ | GABRA1 | P14867 | 4/20 | 0.42 |
| ▸ | GABRB2 | P47870 | 4/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | ALB | P02768 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.42 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.42 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.42 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.42 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.42 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.42 |
| ▸ | HTR2B | P41595 | 1/20 | 0.42 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.42 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | FAAH | O00519 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9416616 | 0.81 | POLB (0.44) | GABRA1GABRB2KDM4ELMNAHPGD | |
| SCHEMBL9264131 | 0.77 | KMT2A (0.47) | GABRA1GABRB2KDM4EHPGDGABRB1 | |
| SCHEMBL9260636 | 0.77 | KDM4E (0.39) | NR4A2GABRA1GABRB2KDM4EHPGD | |
| SCHEMBL9416659 | 0.76 | KDM4E (0.38) | NR4A2GABRA1GABRB2KDM4EHPGD | |
| SCHEMBL9264212 | 0.76 | ADORA3 (0.41) | GABRA1GABRB2KDM4ELMNAALB | |
| Hydrochloric Acid SCHEMBL9263011 | 0.75 | KDM4E (0.37) | NR4A2GABRA1GABRB2KDM4EHPGD | |
| SCHEMBL20893121 | 0.74 | ADORA2A (0.47) | GABRA1GABRB2KDM4ELMNAHPGD | |
| SCHEMBL20893214 | 0.73 | KDM4E (0.44) | GABRA1GABRB2KDM4ELMNAHPGD | |
| SCHEMBL23295676 | 0.73 | KDM4E (0.54) | GABRA1GABRB2KDM4ELMNAHPGD | |
| SCHEMBL9258447 | 0.71 | NR4A2 (0.43) | NR4A2GABRA1GABRB2KDM4ELMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-6271575-A | — | — | None | — | — | JP | disclosed |
| US-5466706-A | Compounds for hypnotics, anxiety or anticonvulsants | SYNTHELABO (FR) | 1995-11-14 | — | — | US | disclosed |
| JP-H06271575-A | 9H-IMIDAZO(1,2-A)BENZIMIDAZOLE-3-ACETOAMIDE DERIVATIVE, ITS PREPARATION AND ITS APPLICATION TO THERAPY | SYNTHELABO SA | 1994-09-27 | — | — | JP | disclosed |
| EP-0607076-A1 | 9H-Imidazo 1,2-a benzimidazole derivatives with GABA activity | SYNTHELABO (FR) | 1994-07-20 | — | — | EP | disclosed |