Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.39 |
| ▸ | ADORA3 | P0DMS8 | 3/20 | 0.37 |
| ▸ | ADORA1 | P30542 | 3/20 | 0.37 |
| ▸ | GABRP | O00591 | 2/20 | 0.37 |
| ▸ | GABRD | O14764 | 2/20 | 0.37 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.37 |
| ▸ | GABRB1 | P18505 | 2/20 | 0.37 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.37 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.37 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.37 |
| ▸ | GABRA3 | P34903 | 2/20 | 0.37 |
| ▸ | GABRA2 | P47869 | 2/20 | 0.37 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.37 |
| ▸ | GABRA4 | P48169 | 2/20 | 0.37 |
| ▸ | GABRE | P78334 | 2/20 | 0.37 |
| ▸ | GABRA6 | Q16445 | 2/20 | 0.37 |
| ▸ | GABRG1 | Q8N1C3 | 2/20 | 0.37 |
| ▸ | GABRG3 | Q99928 | 2/20 | 0.37 |
| ▸ | GABRQ | Q9UN88 | 2/20 | 0.37 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9416659 | 0.88 | KDM4E (0.38) | KDM4EADORA3ADORA1GABRPGABRD | |
| Hydrochloric Acid SCHEMBL9263011 | 0.87 | KDM4E (0.37) | KDM4EADORA3ADORA1GABRPGABRD | |
| SCHEMBL9416648 | 0.82 | ADORA3 (0.44) | KDM4EADORA3ADORA1GABRPGABRD | |
| SCHEMBL9262552 | 0.77 | NR4A2 (0.45) | KDM4EGABRA1GABRB1GABRG2GABRB3 | |
| SCHEMBL9261073 | 0.76 | KMT2A (0.45) | KDM4EADORA3ADORA1GABRPGABRD | |
| SCHEMBL20893121 | 0.72 | ADORA2A (0.47) | KDM4EADORA3ADORA1GABRPGABRD | |
| SCHEMBL20893214 | 0.72 | KDM4E (0.44) | KDM4EADORA3ADORA1GABRPGABRD | |
| SCHEMBL9257773 | 0.71 | ADORA2B (0.37) | KDM4EADORA1NR4A2ALDH1A1MAPT | |
| SCHEMBL9258312 | 0.70 | ADORA1 (0.38) | KDM4EADORA3ADORA1GABRA1GABRB1 | |
| SCHEMBL9080373 | 0.70 | NPSR1 (0.34) | KDM4ENR4A2ALDH1A1MAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5466706-A | Compounds for hypnotics, anxiety or anticonvulsants | SYNTHELABO (FR) | 1995-11-14 | — | — | US | disclosed |
| EP-0607076-A1 | 9H-Imidazo 1,2-a benzimidazole derivatives with GABA activity | SYNTHELABO (FR) | 1994-07-20 | — | — | EP | disclosed |