Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TBXAS1 | P24557 | 4/20 | 0.54 |
| ▸ | QPCT | Q16769 | 3/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | ATM | Q13315 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9267886 | 0.88 | TBXAS1 (0.53) | TBXAS1ALDH1A1MEN1KMT2AMAPT | |
| SCHEMBL9264092 | 0.82 | TBXAS1 (0.70) | TBXAS1QPCTALDH1A1MEN1KMT2A | |
| SCHEMBL9266704 | 0.82 | TBXAS1 (0.70) | TBXAS1QPCTALDH1A1MEN1KMT2A | |
| SCHEMBL8540598 | 0.76 | QPCT (0.53) | TBXAS1QPCTALDH1A1MEN1KMT2A | |
| SCHEMBL8537739 | 0.76 | RAB9A (0.56) | ALDH1A1MEN1KMT2AMAPTTSHR | |
| SCHEMBL8571284 | 0.74 | RAB9A (0.58) | ALDH1A1MEN1KMT2AMAPTLMNA | |
| SCHEMBL14930210 | 0.74 | PDE4B (0.62) | ALDH1A1MEN1KMT2AMAPTLMNA | |
| SCHEMBL15076021 | 0.74 | THRA (0.61) | MEN1KMT2AMAPTLMNANPC1 | |
| SCHEMBL10788695 | 0.74 | SMN1; SMN2 (0.61) | ALDH1A1MEN1KMT2AMAPTLMNA | |
| SCHEMBL21480338 | 0.73 | RAB9A (0.59) | ALDH1A1MEN1KMT2AMAPTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0274867-A2 | Pharmaceutically active compounds | SCHERING CORPORATION (US) | 1988-07-20 | — | — | EP | claimed |
| US-5459144-A | Enterovirus and rhinovirus antiviral, antiinflammatory and antagonist of platelet activating factor | SCHERING CORPORATION (US) | 1995-10-17 | — | — | US | disclosed |
| EP-0274867-B1 | Pharmaceutically active compounds | SCHERING CORP (US) | 1994-04-13 | — | — | EP | disclosed |
| EP-0560407-A1 | Pharmaceutically active compounds | SCHERING CORPORATION (US) | 1993-09-15 | — | — | EP | disclosed |
| WO-1991000858-A1 | PHARMACEUTICALLY ACTIVE COMPOUNDS | SCHERING CORPORATION (US) | 1991-01-24 | — | — | WO | disclosed |
| EP-0407217-A1 | Pharmaceutically active compounds | SCHERING CORPORATION (US) | 1991-01-09 | — | — | EP | disclosed |
| US-4851423-A | Pharmaceutically active compounds | SCHERING CORPORATION (US) | 1989-07-25 | — | — | US | disclosed |
| EP-0274867-A2 | Pharmaceutically active compounds | SCHERING CORPORATION (US) | 1988-07-20 | — | — | EP | disclosed |