Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN9A | Q15858 | 1/20 | 0.51 |
| ▸ | MGLL | Q99685 | 1/20 | 0.47 |
| ▸ | CA12 | O43570 | 1/20 | 0.47 |
| ▸ | BRD4 | O60885 | 1/20 | 0.47 |
| ▸ | BRPF1 | P55201 | 1/20 | 0.47 |
| ▸ | CA9 | Q16790 | 1/20 | 0.47 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.47 |
| ▸ | BRD9 | Q9H8M2 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | APLNR | P35414 | 4/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | METAP2 | P50579 | 1/20 | 0.43 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17505155 | 0.75 | CA12 (0.47) | CA12BRD4BRPF1CA9KAT2B | |
| SCHEMBL9270290 | 0.75 | POLB (0.50) | CA12BRD4BRPF1CA9KAT2B | |
| SCHEMBL29009659 | 0.75 | CA12 (0.47) | SCN9AMGLLCA12BRD4BRPF1 | |
| SCHEMBL23075577 | 0.74 | DRD2 (0.42) | MGLLTSHRALDH1A1KMT2AKDM4E | |
| SCHEMBL11693860 | 0.74 | LMNA (0.53) | MGLLCA12BRD4BRPF1CA9 | |
| SCHEMBL23075579 | 0.73 | ALDH1A1 (0.59) | TSHRALDH1A1KMT2AKDM4EHPGD | |
| SCHEMBL5150754 | 0.72 | KMT2A (0.59) | MGLLCA12BRD4BRPF1CA9 | |
| SCHEMBL30440787 | 0.72 | ALDH1A1 (0.49) | CA12BRD4BRPF1CA9KAT2B | |
| SCHEMBL28181208 | 0.72 | MGLL (0.47) | MGLLCA12CA9ALDH1A1KMT2A | |
| SCHEMBL16296570 | 0.71 | SCN9A (0.61) | SCN9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1995003300-A1 | HETEROARYL QUINOLINES AS INHIBITORS OF LEUKOTRIENE BIOSYNTHESIS | MERCK FROSST CANADA INC. (CA) | 1995-02-02 | — | — | WO | disclosed |