Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 2/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
| ▸ | HTR3A | P46098 | 1/20 | 0.49 |
| ▸ | MPO | P05164 | 1/20 | 0.49 |
| ▸ | SMYD2 | Q9NRG4 | 2/20 | 0.49 |
| ▸ | HTR1D | P28221 | 1/20 | 0.48 |
| ▸ | HTR1B | P28222 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9265034 | 0.99 | PARP1 (0.51) | PARP1KMT2AHTR3AMPOSMYD2 | |
| SCHEMBL8540082 | 0.84 | HTR2A (0.53) | MPO | |
| SCHEMBL8539238 | 0.83 | FAAH (0.51) | MPO | |
| SCHEMBL22578444 | 0.82 | KMT2A (0.66) | KMT2AHTR3ASMYD2HTR1DHTR1B | |
| SCHEMBL9258556 | 0.81 | ADRA2A (0.73) | — | |
| SCHEMBL9261940 | 0.81 | KMT2A (0.57) | KMT2A | |
| SCHEMBL9264310 | 0.80 | ADRA2A (0.75) | — | |
| SCHEMBL9268126 | 0.78 | KMT2A (0.49) | KMT2AMPOHTR1DALDH1A1CYP1A2 | |
| SCHEMBL9264670 | 0.76 | SNCA (0.58) | KMT2AHTR1DHTR1B | |
| SCHEMBL9257648 | 0.75 | HTR7 (0.68) | KMT2AMPOHTR1DHTR1BHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5418237-A | Indole derivatives | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1995-05-23 | — | — | US | disclosed |