Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | MPO | P05164 | 2/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | HTR1D | P28221 | 1/20 | 0.48 |
| ▸ | SNCA | P37840 | 9/20 | 0.48 |
| ▸ | GFER | P55789 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | ACHE | P22303 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.46 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9261940 | 0.84 | KMT2A (0.57) | KMT2APOLBHSD17B10SNCAGFER | |
| SCHEMBL8537746 | 0.83 | FAAH (0.54) | HTR1D | |
| SCHEMBL9265034 | 0.79 | PARP1 (0.51) | KMT2AMPOHTR1DALDH1A1 | |
| SCHEMBL9263285 | 0.78 | PARP1 (0.52) | KMT2AMPOCYP1A2CYP2D6CYP2C9 | |
| SCHEMBL9264670 | 0.78 | SNCA (0.58) | KMT2AHTR1DSNCAACHEMAPK1 | |
| SCHEMBL9264578 | 0.77 | ADRA2A (0.70) | — | |
| SCHEMBL8557448 | 0.77 | GPR84 (0.62) | KMT2APOLBHSD17B10CYP1A2HTR1D | |
| SCHEMBL9257648 | 0.76 | HTR7 (0.68) | KMT2AMPOHSD17B10CYP1A2CYP2D6 | |
| SCHEMBL8555452 | 0.75 | HTR7 (0.71) | KMT2AMPOHSD17B10CYP1A2CYP2D6 | |
| SCHEMBL9097064 | 0.75 | HSD17B10 (0.56) | KMT2APOLBMPOHSD17B10CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5418237-A | Indole derivatives | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1995-05-23 | — | — | US | disclosed |