Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPM8 | Q7Z2W7 | 4/20 | 0.58 |
| ▸ | DYRK3 | O43781 | 1/20 | 0.46 |
| ▸ | CLK1 | P49759 | 1/20 | 0.46 |
| ▸ | CLK2 | P49760 | 1/20 | 0.46 |
| ▸ | CLK3 | P49761 | 1/20 | 0.46 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.46 |
| ▸ | DYRK2 | Q92630 | 1/20 | 0.46 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.46 |
| ▸ | DYRK4 | Q9NR20 | 1/20 | 0.46 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.46 |
| ▸ | CHRM5 | P08912 | 2/20 | 0.44 |
| ▸ | UBE2M | P61081 | 1/20 | 0.42 |
| ▸ | DCUN1D1 | Q96GG9 | 1/20 | 0.42 |
| ▸ | IKBKB | O14920 | 1/20 | 0.42 |
| ▸ | CHUK | O15111 | 1/20 | 0.42 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.42 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.42 |
| ▸ | IRAK4 | Q9NWZ3 | 4/20 | 0.41 |
| ▸ | CHKA | P35790 | 1/20 | 0.41 |
| ▸ | CHKB | Q9Y259 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL926043 | 0.80 | TRPM8 (0.57) | TRPM8IRAK4EPHX1NPC1RAB9A | |
| SCHEMBL2628739 | 0.78 | TRPM8 (0.67) | TRPM8EPHX1MEN1NPC1RAB9A | |
| SCHEMBL14565718 | 0.78 | TRPM8 (0.67) | TRPM8EPHX1MEN1NPC1RAB9A | |
| SCHEMBL2628764 | 0.78 | TRPM8 (0.65) | TRPM8EPHX1MEN1KMT2A | |
| SCHEMBL15133466 | 0.78 | TRPM8 (0.62) | TRPM8EPHX1NPC1RAB9A | |
| SCHEMBL2628672 | 0.77 | TRPM8 (0.75) | TRPM8EPHX1MEN1NPC1RAB9A | |
| SCHEMBL4817319 | 0.77 | TRPM8 (0.75) | TRPM8EPHX1MEN1NPC1RAB9A | |
| SCHEMBL10073486 | 0.77 | TRPM8 (0.75) | TRPM8EPHX1MEN1NPC1RAB9A | |
| SCHEMBL4820732 | 0.77 | TRPM8 (0.75) | TRPM8EPHX1MEN1NPC1RAB9A | |
| SCHEMBL5448215 | 0.77 | TRPM8 (0.64) | TRPM8EPHX1MEN1NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7868004-B2 | Menthane carboxamide derivatives having cooling properties | GIVAUDAN S.A. (CH) | 2011-01-11 | — | — | US | disclosed |
| EP-1853565-B1 | MENTHANE CARBOXAMIDE DERIVATIVES HAVING COOLING PROPERTIES | GIVAUDAN SA (CH) | 2010-09-22 | — | — | EP | disclosed |
| US-20080305051-A1 | Menthane Carboxamide Derivatives Having Cooling Properties | GIVAUDAN S.A. (CH) | 2008-12-11 | — | — | US | disclosed |
| EP-1853565-A1 | MENTHANE CARBOXAMIDE DERIVATIVES HAVING COOLING PROPERTIES | Givaudan SA (CH) | 2007-11-14 | — | — | EP | disclosed |
| WO-2006092074-A1 | MENTHANE CARBOXAMIDE DERIVATIVES HAVING COOLING PROPERTIES | GIVAUDAN SA (CH) | 2006-09-08 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080305051-A1 | Menthane Carboxamide Derivatives Having Cooling Properties | MDH2, ME2, H1-0 | TRPM8 72/4885DYRK3 192/4885CLK1 1094/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.