Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPM8 | Q7Z2W7 | 4/20 | 0.57 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.40 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.38 |
| ▸ | FPR3 | P25089 | 1/20 | 0.38 |
| ▸ | FPR2 | P25090 | 1/20 | 0.38 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.36 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | NAMPT | P43490 | 1/20 | 0.35 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.35 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.35 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.35 |
| ▸ | AAK1 | Q2M2I8 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL926378 | 0.80 | TRPM8 (0.58) | TRPM8NPC1RAB9ASMN1; SMN2EPHX1 | |
| SCHEMBL2628739 | 0.78 | TRPM8 (0.67) | TRPM8NPC1RAB9AEPHX1 | |
| SCHEMBL14565718 | 0.78 | TRPM8 (0.67) | TRPM8NPC1RAB9AEPHX1 | |
| SCHEMBL926249 | 0.77 | TRPM8 (0.49) | TRPM8EPHX1TRPV1CYP19A1P2RX4 | |
| SCHEMBL29532603 | 0.77 | TRPM8 (0.49) | TRPM8EPHX1TRPV1CYP19A1P2RX4 | |
| SCHEMBL2628764 | 0.77 | TRPM8 (0.65) | TRPM8EPHX1TRPV1 | |
| SCHEMBL925829 | 0.76 | TRPM8 (0.61) | TRPM8NPC1RAB9ASMN1; SMN2LMNA | |
| SCHEMBL2628765 | 0.76 | TRPM8 (0.61) | TRPM8NPC1RAB9ASMN1; SMN2LMNA | |
| SCHEMBL2628672 | 0.76 | TRPM8 (0.75) | TRPM8NPC1RAB9ASMN1; SMN2EPHX1 | |
| SCHEMBL4817319 | 0.76 | TRPM8 (0.75) | TRPM8NPC1RAB9ASMN1; SMN2EPHX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2155158-B1 | PERSONAL LUBRICANT COMPOSITION | LRC PRODUCTS (GB) | 2019-08-21 | — | — | EP | disclosed |
| US-7868004-B2 | Menthane carboxamide derivatives having cooling properties | GIVAUDAN S.A. (CH) | 2011-01-11 | — | — | US | disclosed |
| EP-1853565-B1 | MENTHANE CARBOXAMIDE DERIVATIVES HAVING COOLING PROPERTIES | GIVAUDAN SA (CH) | 2010-09-22 | — | — | EP | disclosed |
| EP-2155158-A1 | PERSONAL LUBRICANT COMPOSITION | LRC Products Limited (GB) | 2010-02-24 | — | — | EP | disclosed |
| WO-2008152374-A1 | PERSONAL LUBRICANT COMPOSITION | LRC PRODUCTS LIMITED (GB) | 2008-12-18 | — | — | WO | disclosed |
| US-20080305051-A1 | Menthane Carboxamide Derivatives Having Cooling Properties | GIVAUDAN S.A. (CH) | 2008-12-11 | — | — | US | disclosed |
| EP-1853565-A1 | MENTHANE CARBOXAMIDE DERIVATIVES HAVING COOLING PROPERTIES | Givaudan SA (CH) | 2007-11-14 | — | — | EP | disclosed |
| WO-2006092074-A1 | MENTHANE CARBOXAMIDE DERIVATIVES HAVING COOLING PROPERTIES | GIVAUDAN SA (CH) | 2006-09-08 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080305051-A1 | Menthane Carboxamide Derivatives Having Cooling Properties | MDH2, ME2, H1-0 | TRPM8 72/4885NPC1 4322/4885RAB9A 2348/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.