Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.46 |
| ▸ | ATM | Q13315 | 1/20 | 0.46 |
| ▸ | CA12 | O43570 | 1/20 | 0.46 |
| ▸ | CA1 | P00915 | 1/20 | 0.46 |
| ▸ | CA2 | P00918 | 1/20 | 0.46 |
| ▸ | CA7 | P43166 | 1/20 | 0.46 |
| ▸ | CA9 | Q16790 | 1/20 | 0.46 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.45 |
| ▸ | POLB | P06746 | 3/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.45 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.44 |
| ▸ | MGLL | Q99685 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL9271468 | 0.99 | KMT2A (0.45) | KMT2AATMCA12CA1CA2 | |
| SCHEMBL9265627 | 0.81 | ALDH1A1 (0.51) | KMT2AALDH1A1POLBMEN1SMN1; SMN2 | |
| SCHEMBL8711485 | 0.81 | PAX8 (0.48) | ATMPOLBHSD11B1NPC1RAB9A | |
| SCHEMBL9257879 | 0.81 | CHRNB2 (0.46) | KMT2ACA12CA1CA2CA7 | |
| SCHEMBL6336383 | 0.81 | CHRNA7 (0.57) | KMT2AALDH1A1POLBMGLLHPGD | |
| SCHEMBL6319408 | 0.81 | CHRNB2 (0.61) | ALDH1A1HPGDHTT | |
| Hydrochloric Acid SCHEMBL9272008 | 0.80 | CHRNB2 (0.45) | CA12CA1CA2CA7CA9 | |
| SCHEMBL4042905 | 0.80 | CA12 (0.62) | KMT2ACA12CA1CA2CA7 | |
| SCHEMBL14236800 | 0.78 | RAB9A (0.63) | KMT2AATMCA12CA1CA2 | |
| SCHEMBL17055124 | 0.76 | CA1 (0.56) | KMT2AATMCA12CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5468858-A | Sudden death syndrome | THE BOARD OF REGENTS OF OKLAHOMA STATE UNIVERSITY PHYSICAL SCIENCES (US) | 1995-11-21 | — | — | US | disclosed |