Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 1/20 | 0.36 |
| ▸ | AGTR1 | P30556 | 3/20 | 0.36 |
| ▸ | AGTR2 | P50052 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9265478 | 0.77 | AGTR1 (0.56) | AGTR1AGTR2MEN1ALDH1A1KMT2A | |
| SCHEMBL7303815 | 0.73 | AGTR1 (0.52) | AGTR1AGTR2 | |
| SCHEMBL9171970 | 0.73 | ITGB1 (0.33) | AGTR1AGTR2MEN1ALDH1A1KMT2A | |
| SCHEMBL9543810 | 0.73 | PPARG (0.61) | PPARGAGTR1AGTR2 | |
| SCHEMBL9851462 | 0.73 | BRD4 (0.42) | AGTR1AGTR2ALDH1A1 | |
| SCHEMBL7308562 | 0.72 | AGTR1 (0.47) | AGTR1AGTR2 | |
| SCHEMBL3339360 | 0.72 | PPARG (0.41) | PPARGAGTR1AGTR2 | |
| SCHEMBL9427506 | 0.72 | CCR2 (0.33) | PPARGAGTR1AGTR2 | |
| SCHEMBL7304485 | 0.71 | AGTR1 (0.53) | AGTR1 | |
| SCHEMBL9231253 | 0.71 | AGTR1 (0.44) | PPARGAGTR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5407942-A | For treating hypertension, atherosclerosis | BAYER AKTIENGESELLSCHAFT (DE) | 1995-04-18 | — | — | US | disclosed |