Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.40 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.31 |
| ▸ | RXRA | P19793 | 1/20 | 0.30 |
| ▸ | RXRB | P28702 | 1/20 | 0.30 |
| ▸ | RXRG | P48443 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9351882 | 0.83 | MEN1 (0.38) | L3MBTL1MEN1KMT2A | |
| SCHEMBL9269153 | 0.82 | L3MBTL1 (0.49) | L3MBTL1CYP2C19MEN1KMT2ANPSR1 | |
| SCHEMBL24372709 | 0.81 | L3MBTL1 (0.37) | L3MBTL1CYP2C19MEN1RAB9AKMT2A | |
| SCHEMBL4734850 | 0.81 | L3MBTL1 (0.50) | L3MBTL1MEN1RAB9AKMT2ANPSR1 | |
| SCHEMBL2653825 | 0.76 | L3MBTL1 (0.44) | L3MBTL1MEN1RAB9AKMT2ANPSR1 | |
| SCHEMBL386837 | 0.74 | ALDH1A1 (0.48) | CYP2C19MEN1RAB9AKMT2ACYP1A2 | |
| SCHEMBL14030717 | 0.73 | RAB9A (0.55) | CYP2C19MEN1RAB9AKMT2ANPSR1 | |
| SCHEMBL8794474 | 0.72 | RAB9A (0.36) | L3MBTL1CYP2C19RAB9ANPSR1CYP1A2 | |
| SCHEMBL25773118 | 0.72 | L3MBTL1 (0.33) | L3MBTL1CYP2C19RAB9ANPSR1CYP1A2 | |
| SCHEMBL14488840 | 0.69 | CYP3A4 (0.47) | L3MBTL1GABRA1GABRB2MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5476944-A | Inhibitors or stimulators of superoxide generation; may also inhibit cyclooxygenase and/or 5-lipoxygenase; useful in therapeutic or prophylactic treatment of disease conditions | G. D. SEARLE & CO. (US) | 1995-12-19 | — | — | US | disclosed |
| EP-0613463-A1 | DERIVATIVES OF CYCLIC PHENOLIC THIOETHERS AS INHIBITORS OR STIMULATORS OF SUPEROXIDE GENERATION | G.D. SEARLE & CO. (US) | 1994-09-07 | — | — | EP | disclosed |