Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | CSF1R | P07333 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.32 |
| ▸ | PARP1 | P09874 | 2/20 | 0.32 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.31 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | PIM1 | P11309 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | CDK4 | P11802 | 1/20 | 0.31 |
| ▸ | CCND1 | P24385 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | TNKS | O95271 | 1/20 | 0.30 |
| ▸ | PARP15 | Q460N3 | 1/20 | 0.30 |
| ▸ | PARP14 | Q460N5 | 1/20 | 0.30 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9269032 | 0.76 | CSF1R (0.42) | PTGS2MEN1KMT2ACSF1RKDM4E | |
| SCHEMBL9270496 | 0.73 | MEN1 (0.37) | MEN1KMT2AKDM4EPARP1LMNA | |
| SCHEMBL9270253 | 0.71 | ALDH1A1 (0.43) | PTGS2MEN1KMT2ACSF1RKDM4E | |
| SCHEMBL9557849 | 0.70 | KDM4E (0.48) | PTGS2MEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL9266250 | 0.70 | KMT2A (0.53) | MEN1KMT2AKDM4EALDH1A1LMNA | |
| SCHEMBL9270566 | 0.70 | PRNP (0.36) | MEN1KMT2ACSF1RPIM1LMNA | |
| SCHEMBL9266144 | 0.67 | KDM4E (0.42) | MEN1KMT2AKDM4EALDH1A1PARP1 | |
| SCHEMBL11284238 | 0.65 | PTGS2 (0.50) | PTGS2MEN1KMT2ACSF1RALDH1A1 | |
| SCHEMBL9182334 | 0.63 | KMT2A (0.48) | PTGS2MEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL9267768 | 0.63 | DAO (0.39) | KDM4EALDH1A1PARP1TDP1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1995024395-A1 | QUINOLINE DERIVATIVES AS IMMUNOMODULATORS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1995-09-14 | — | — | WO | disclosed |