Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.51 |
| ▸ | LMNA | P02545 | 2/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | HTR1A | P08908 | 3/20 | 0.42 |
| ▸ | ADRA1D | P25100 | 2/20 | 0.42 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.42 |
| ▸ | ADRA1B | P35368 | 2/20 | 0.42 |
| ▸ | HTR7 | P34969 | 1/20 | 0.42 |
| ▸ | ACHE | P22303 | 1/20 | 0.41 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9266592 | 0.84 | ADRB2 (0.41) | NPSR1KDM4EALDH1A1LMNATDP1 | |
| SCHEMBL9266739 | 0.83 | ADRA1A (0.40) | NPSR1KDM4EALDH1A1LMNATDP1 | |
| SCHEMBL29074501 | 0.83 | L3MBTL1 (0.37) | NPSR1KDM4EALDH1A1LMNATDP1 | |
| SCHEMBL6275145 | 0.81 | LMNA (0.53) | NPSR1KDM4EALDH1A1LMNATDP1 | |
| SCHEMBL2345631 | 0.81 | L3MBTL1 (0.61) | NPSR1KDM4EALDH1A1LMNATDP1 | |
| SCHEMBL9270489 | 0.81 | L3MBTL1 (0.43) | NPSR1KDM4EALDH1A1LMNATDP1 | |
| SCHEMBL9262266 | 0.80 | CYP1A2 (0.51) | NPSR1KDM4EALDH1A1LMNATDP1 | |
| SCHEMBL4631786 | 0.79 | LMNA (0.54) | NPSR1KDM4EALDH1A1LMNATDP1 | |
| SCHEMBL6274367 | 0.78 | TDP1 (0.48) | NPSR1KDM4EALDH1A1LMNATDP1 | |
| SCHEMBL25925300 | 0.78 | NPSR1 (0.64) | NPSR1KDM4EALDH1A1LMNATDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5436264-A | Adrenergic blocking agents for vasoconstriction and hypotensive agents | SYNTEX (U.S.A.) INC. (US) | 1995-07-25 | — | — | US | disclosed |