Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | RIOK2 | Q9BVS4 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | PSMB8 | P28062 | 2/20 | 0.40 |
| ▸ | PSMB5 | P28074 | 2/20 | 0.40 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.40 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18461814 | 0.83 | LMNA (0.47) | LMNAMEN1KMT2AGAAL3MBTL1 | |
| SCHEMBL2655186 | 0.82 | CA2 (0.44) | LMNAKMT2AGAAALDH1A1KDM4E | |
| SCHEMBL6977259 | 0.82 | HDAC1 (0.43) | LMNAMEN1KMT2AALDH1A1 | |
| SCHEMBL1259978 | 0.81 | LMNA (0.46) | LMNAMEN1KMT2AGAAL3MBTL1 | |
| SCHEMBL969589 | 0.81 | HPGD (0.55) | LMNAMEN1KMT2AGAAL3MBTL1 | |
| SCHEMBL12900623 | 0.81 | LMNA (0.46) | LMNAMEN1KMT2AGAAL3MBTL1 | |
| SCHEMBL9724448 | 0.80 | GAA (0.50) | LMNAMEN1KMT2AGAAL3MBTL1 | |
| SCHEMBL4684430 | 0.79 | LMNA (0.45) | LMNAMEN1KMT2AGAAL3MBTL1 | |
| Hydrochloric Acid SCHEMBL2530255 | 0.79 | HPGD (0.53) | LMNAMEN1KMT2AGAAL3MBTL1 | |
| SCHEMBL2702346 | 0.79 | CA2 (0.52) | LMNAMEN1KMT2AGAAL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5405873-A | Antilipemic, anticholesterol agents; treating arterio-sclerosis | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1995-04-11 | — | — | US | disclosed |
| EP-0587430-A1 | Substituted acetamide derivatives for treatment of hypocholesterolaemia, hyperlipaemia and arteriosclerosis | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1994-03-16 | — | — | EP | disclosed |