Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | ATM | Q13315 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | GLA | P06280 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | OGG1 | O15527 | 1/20 | 0.37 |
| ▸ | LIMK1 | P53667 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9267044 | 0.80 | LMNA (0.38) | LMNAMAPK1ALDH1A1MAPTHSD17B10 | |
| SCHEMBL1269967 | 0.80 | LMNA (0.63) | LMNAMAPK1ALDH1A1MAPTHSD17B10 | |
| SCHEMBL9033196 | 0.80 | LMNA (0.46) | LMNAMAPK1ALDH1A1MAPTHSD17B10 | |
| SCHEMBL9380510 | 0.78 | LMNA (0.44) | LMNAMAPK1ALDH1A1MAPTHSD17B10 | |
| SCHEMBL9033191 | 0.78 | LMNA (0.44) | LMNAMAPK1ALDH1A1MAPTHSD17B10 | |
| SCHEMBL9034125 | 0.77 | NPC1 (0.42) | LMNAMAPK1ALDH1A1MAPTGAA | |
| SCHEMBL9032895 | 0.76 | RAB9A (0.43) | LMNAMAPK1ALDH1A1MAPTHSD17B10 | |
| SCHEMBL7987786 | 0.75 | MAPT (0.45) | LMNAMAPK1ALDH1A1MAPTHSD17B10 | |
| SCHEMBL9032132 | 0.75 | HIF1A (0.44) | LMNAMAPK1ALDH1A1MAPTGAA | |
| SCHEMBL9393951 | 0.73 | MCL1 (0.58) | LMNAMAPK1OGG1LIMK1PTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1995014015-A1 | BENZOTHIOPHENE DERIVATIVES POSSESSING A METHOXYIMINO SUBSTITUENT AS MICROBICIDES | CIBA-GEIGY AG (CH) | 1995-05-26 | — | — | WO | disclosed |