Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | GAA | P10253 | 2/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.45 |
| ▸ | NPC1 | O15118 | 2/20 | 0.45 |
| ▸ | TSHR | P16473 | 2/20 | 0.45 |
| ▸ | RAB9A | P51151 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | F2 | P00734 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.44 |
| ▸ | MCL1 | Q07820 | 5/20 | 0.44 |
| ▸ | LIMK1 | P53667 | 2/20 | 0.44 |
| ▸ | IKBKB | O14920 | 1/20 | 0.44 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | OGG1 | O15527 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | GLA | P06280 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9393951 | 0.85 | MCL1 (0.58) | LMNAMAPK1MCL1LIMK1IKBKB | |
| SCHEMBL1269967 | 0.83 | LMNA (0.63) | MAPTKMT2AGAAALOX15NPC1 | |
| SCHEMBL7984505 | 0.82 | MCL1 (0.49) | MAPTKMT2AGAAALOX15NPC1 | |
| SCHEMBL22909024 | 0.80 | ALDH1A1 (0.59) | MAPTKMT2AGAATSHRSMN1; SMN2 | |
| SCHEMBL29513021 | 0.80 | ALDH1A1 (0.59) | MAPTKMT2AGAATSHRSMN1; SMN2 | |
| SCHEMBL7985027 | 0.80 | MCL1 (0.51) | MAPTKMT2AGAAALOX15NPC1 | |
| SCHEMBL2503631 | 0.77 | PTGS2 (0.56) | MAPTKMT2AGAAALOX15NPC1 | |
| SCHEMBL9033196 | 0.77 | LMNA (0.46) | MAPTKMT2AGAAALOX15NPC1 | |
| SCHEMBL2610250 | 0.75 | RXFP1 (0.61) | MAPTKMT2AGAAALOX15NPC1 | |
| SCHEMBL9601620 | 0.75 | RAB9A (0.61) | MAPTKMT2AGAAALOX15NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001007431-A2 | BENZOTHIOPHENE DERIVATIVES | ELI LILLY AND COMPANY (US) | 2001-02-01 | — | — | WO | disclosed |