Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.43 |
| ▸ | ATM | Q13315 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | GLA | P06280 | 1/20 | 0.43 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.40 |
| ▸ | OGG1 | O15527 | 1/20 | 0.37 |
| ▸ | LIMK1 | P53667 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 2/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | MAOB | P27338 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9380510 | 1.00 | LMNA (0.44) | LMNAMAPK1ALDH1A1HSD17B10MAPT | |
| SCHEMBL9033196 | 0.90 | LMNA (0.46) | LMNAMAPK1ALDH1A1HSD17B10MAPT | |
| SCHEMBL9219336 | 0.80 | MAPK1 (0.44) | LMNAMAPK1ALDH1A1HSD17B10MAPT | |
| SCHEMBL1269967 | 0.80 | LMNA (0.63) | LMNAMAPK1ALDH1A1HSD17B10MAPT | |
| SCHEMBL9267367 | 0.78 | LMNA (0.44) | LMNAMAPK1ALDH1A1HSD17B10MAPT | |
| SCHEMBL7987786 | 0.75 | MAPT (0.45) | LMNAMAPK1ALDH1A1HSD17B10MAPT | |
| SCHEMBL9380388 | 0.75 | SMN1; SMN2 (0.42) | LMNAMAPK1ALDH1A1HSD17B10MAPT | |
| SCHEMBL9212799 | 0.74 | LMNA (0.48) | LMNAMAPK1ALDH1A1HSD17B10MAPT | |
| SCHEMBL9393951 | 0.73 | MCL1 (0.58) | LMNAMAPK1PTGS2OGG1LIMK1 | |
| SCHEMBL22909024 | 0.72 | ALDH1A1 (0.59) | LMNAMAPK1ALDH1A1HSD17B10MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0621864-B1 | 2-(2-BENZO(b)THIENYL)-3-METHOXYACRYLATE AND -2-IMINOACETATE DERIVATIVES TO BE USED AS PESTICIDES | CIBA GEIGY AG (CH) | 1996-12-27 | — | — | EP | disclosed |
| EP-0621864-A1 | 2-(2-BENZO(b)THIENYL)-3-METHOXYACRYLATE AND -2-IMINOACETATE DERIVATIVES TO BE USED AS PESTICIDES. | CIBA GEIGY AG (CH) | 1994-11-02 | — | — | EP | disclosed |
| WO-1993008183-A1 | 2-(2-BENZO(b)THIENYL)-3-METHOXYACRYLATE AND -2-IMINOACETATE DERIVATIVES TO BE USED AS PESTICIDES | CIBA-GEIGY AG (CH) | 1993-04-29 | — | — | WO | disclosed |