Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | PDE4B | Q07343 | 5/20 | 0.43 |
| ▸ | PDE4D | Q08499 | 5/20 | 0.43 |
| ▸ | PDE4A | P27815 | 5/20 | 0.43 |
| ▸ | PDE4C | Q08493 | 4/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | FEN1 | P39748 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10427752 | 0.82 | KMT2A (0.50) | MAPTCYP1A2CYP2C19MEN1KMT2A | |
| SCHEMBL7272901 | 0.78 | PDE4A (0.48) | MAPTCYP1A2CYP2C19MEN1KMT2A | |
| SCHEMBL9799559 | 0.78 | CYP1A2 (0.44) | MAPTCYP1A2CYP2C19MEN1KMT2A | |
| Water SCHEMBL9715615 | 0.76 | MAPT (0.42) | MAPTCYP1A2CYP2C19MEN1KMT2A | |
| SCHEMBL9348283 | 0.76 | MAPT (0.46) | MAPTCYP1A2CYP2C19MEN1KMT2A | |
| Water SCHEMBL10427748 | 0.76 | MAPT (0.44) | MAPTCYP1A2CYP2C19MEN1KMT2A | |
| SCHEMBL7273701 | 0.75 | PDE4A (0.76) | MAPTCYP1A2CYP2C19MEN1KMT2A | |
| SCHEMBL9348307 | 0.75 | CYP1A2 (0.46) | MAPTCYP1A2CYP2C19MEN1KMT2A | |
| SCHEMBL10427749 | 0.74 | MEN1 (0.42) | MAPTCYP1A2CYP2C19MEN1KMT2A | |
| SCHEMBL9535601 | 0.72 | MAPT (0.50) | MAPTCYP1A2CYP2C19MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-7304775-A | — | — | None | — | — | JP | disclosed |
| JP-H07304775-A | NAPHTHYRIDINE AND PYRIDOPYRAZINE DERIVATIVE | OTSUKA PHARMACEUT FACTORY INC | 1995-11-21 | — | — | JP | disclosed |