SCHEMBL9268162

SCHEMBL9268162

CC(C)(C)OOC(=O)COCC(=O)OC(C)(C)C

nearest known ligand 0.34

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
CYP2D6 P10635 1/20 0.34
ALDH1A1 P00352 1/20 0.33
TSHR P16473 1/20 0.33
HSD17B10 Q99714 1/20 0.33
TDP1 Q9NUW8 1/20 0.33
HDAC3 O15379 1/20 0.33
HDAC1 Q13547 1/20 0.33
HDAC2 Q92769 1/20 0.33
HDAC8 Q9BY41 1/20 0.33
HDAC6 Q9UBN7 1/20 0.33
LATS1 O95835 1/20 0.32
DGAT1 O75907 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6688426 0.87 DGAT1 (0.37) CYP2D6TDP1HDAC3HDAC1HDAC2
SCHEMBL9011776 0.81 TSHR (0.34) ALDH1A1TSHRHSD17B10TDP1
SCHEMBL25288699 0.78 VCAM1 (0.38) CYP2D6TSHRHDAC3HDAC1HDAC2
SCHEMBL19341662 0.78 CES2 (0.38) CYP2D6ALDH1A1TSHRHSD17B10HDAC3
SCHEMBL13323676 0.78 DGAT1 (0.34) CYP2D6TDP1HDAC3HDAC1HDAC2
SCHEMBL13907508 0.78 APLNR (0.36) CYP2D6ALDH1A1HSD17B10TDP1HDAC3
SCHEMBL15679518 0.77 MAPK1 (0.34) CYP2D6ALDH1A1HDAC3HDAC1HDAC2
SCHEMBL14532262 0.77 CYP2D6 (0.32) CYP2D6HDAC3HDAC1HDAC2HDAC8
SCHEMBL20535616 0.76 APLNR (0.35) CYP2D6ALDH1A1HSD17B10TDP1HDAC3
SCHEMBL20535618 0.76 APLNR (0.35) CYP2D6ALDH1A1HSD17B10TDP1HDAC3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-7196714-A None JP disclosed
JP-H07196714-A POLYMERIZATION OF VINYL CHLORIDE NIPPON OIL & FATS CO LTD 1995-08-01 JP disclosed