SCHEMBL9268363

SCHEMBL9268363

CC(c1cccc(Cl)c1)c1ccc(O)c(C(=O)O)c1

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA1 P00915 2/20 0.56
CA2 P00918 2/20 0.56
ALDH1A1 P00352 3/20 0.49
KDM4E B2RXH2 2/20 0.49
HPGD P15428 2/20 0.49
HSD17B10 Q99714 2/20 0.49
TDP1 Q9NUW8 2/20 0.49
CYP2C9 P11712 1/20 0.49
MEN1 O00255 1/20 0.49
CYP2C19 P33261 1/20 0.49
KMT2A Q03164 1/20 0.49
GRM1 Q13255 1/20 0.49
TRPM8 Q7Z2W7 1/20 0.47
TSHR P16473 1/20 0.47
CSNK2A1 P68400 1/20 0.44
ACMSD Q8TDX5 3/20 0.43
CA12 O43570 1/20 0.42
ALOX5 P09917 1/20 0.42
PTGS2 P35354 1/20 0.42
CA7 P43166 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL658651 0.86 KDM4E (0.56) CA1CA2ALDH1A1KDM4EHPGD
SCHEMBL1373696 0.86 KDM4E (0.56) CA1CA2ALDH1A1KDM4EHPGD
SCHEMBL2833452 0.86 KDM4E (0.62) CA1CA2ALDH1A1KDM4EHPGD
SCHEMBL11755689 0.85 CA1 (0.53) CA1CA2ALDH1A1KDM4EHPGD
SCHEMBL5964731 0.84 KDM4E (0.54) CA1CA2ALDH1A1KDM4EHPGD
SCHEMBL5697821 0.84 CSNK2A1 (0.57) CA1CA2ALDH1A1KDM4EHPGD
SCHEMBL5884677 0.82 ACMSD (0.62) ALDH1A1KDM4EHPGDHSD17B10TDP1
SCHEMBL10692626 0.80 KDM4E (0.47) CA1CA2ALDH1A1KDM4EHPGD
SCHEMBL8428483 0.80 CA1 (0.58) CA1CA2ALDH1A1KDM4EHPGD
SCHEMBL9160643 0.79 HNF4A (0.64) ALDH1A1KDM4EHPGDHSD17B10TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0680626-A1 PHOTOPOLYMERIZABLE COMPOSITION OF HIGH SENSITIVITY AND METHOD FOR OBTAINING IMAGES THEREWITH AGFA-GEVAERT N.V. (BE) 1995-11-08 EP disclosed
WO-1994017452-A1 PHOTOPOLYMERIZABLE COMPOSITION OF HIGH SENSITIVITY AND METHOD FOR OBTAINING IMAGES THEREWITH AGFA-GEVAERT NAAMLOZE VENNOOTSCHAP (BE) 1994-08-04 WO disclosed
EP-0465756-A1 Heat-sensitive recording medium HONSHU PAPER CO., LTD. (JP) 1992-01-15 EP disclosed
EP-0308978-A2 Multi-color heat sensitive recording material KANZAKI PAPER MANUFACTURING CO., LTD. (JP) 1989-03-29 EP disclosed