Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 2/20 | 0.62 |
| ▸ | NPC1 | O15118 | 1/20 | 0.62 |
| ▸ | POLB | P06746 | 1/20 | 0.62 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.55 |
| ▸ | GAA | P10253 | 2/20 | 0.52 |
| ▸ | LMNA | P02545 | 2/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.47 |
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | NPY1R | P25929 | 1/20 | 0.47 |
| ▸ | NPY2R | P49146 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | EPHX2 | P34913 | 4/20 | 0.46 |
| ▸ | CNR1 | P21554 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.44 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.44 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9269081 | 0.88 | RAB9A (0.65) | RAB9ANPC1POLBL3MBTL1GAA | |
| SCHEMBL16866144 | 0.81 | NPC1 (0.86) | RAB9ANPC1POLBL3MBTL1GAA | |
| SCHEMBL2750640 | 0.79 | RAB9A (0.97) | RAB9ANPC1POLBL3MBTL1GAA | |
| SCHEMBL27267057 | 0.78 | RAB9A (1.00) | RAB9ANPC1POLBL3MBTL1GAA | |
| SCHEMBL27264917 | 0.78 | RAB9A (1.00) | RAB9ANPC1POLBL3MBTL1GAA | |
| SCHEMBL9271582 | 0.77 | MAPT (0.58) | POLBGAALMNAALDH1A1KMT2A | |
| SCHEMBL9270646 | 0.77 | RAB9A (0.67) | RAB9ANPC1LMNASMN1; SMN2ALDH1A1 | |
| SCHEMBL23573490 | 0.76 | NPC1 (0.77) | RAB9ANPC1POLBL3MBTL1GAA | |
| SCHEMBL23573491 | 0.76 | NPC1 (0.77) | RAB9ANPC1POLBL3MBTL1GAA | |
| SCHEMBL9274428 | 0.75 | KMT2A (0.62) | RAB9ANPC1SMN1; SMN2ALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5420164-A | Enzyme inhibitors | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1995-05-30 | — | — | US | disclosed |
| EP-0507291-A1 | Cyclohexylurea compounds | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1992-10-07 | — | — | EP | disclosed |