Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIN1 | Q13526 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | CASP3 | P42574 | 4/20 | 0.49 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | MDM4 | O15151 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30896048 | 0.89 | CASP3 (0.52) | PIN1KMT2ACASP3EPHX2CYP3A4 | |
| SCHEMBL118209 | 0.89 | CASP3 (0.52) | PIN1KMT2ACASP3EPHX2CYP3A4 | |
| SCHEMBL30896049 | 0.89 | CASP3 (0.52) | PIN1KMT2ACASP3EPHX2CYP3A4 | |
| SCHEMBL14019298 | 0.89 | POLB (0.51) | PIN1KMT2ACASP3EPHX2CYP3A4 | |
| SCHEMBL6038102 | 0.89 | CASP3 (0.52) | PIN1KMT2ACASP3EPHX2CYP3A4 | |
| SCHEMBL1486287 | 0.89 | CASP3 (0.52) | PIN1KMT2ACASP3EPHX2CYP3A4 | |
| SCHEMBL1486214 | 0.89 | CASP3 (0.52) | PIN1KMT2ACASP3EPHX2CYP3A4 | |
| SCHEMBL119497 | 0.89 | CASP3 (0.52) | PIN1KMT2ACASP3EPHX2CYP3A4 | |
| SCHEMBL1564185 | 0.89 | CASP3 (0.52) | PIN1KMT2ACASP3EPHX2CYP3A4 | |
| SCHEMBL31546599 | 0.89 | POLB (0.51) | PIN1KMT2ACASP3EPHX2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240229026-A1 | CHIRAL CONTROL | WAVE LIFE SCIENCES LTD. (SG) | 2024-07-11 | — | — | US | disclosed |
| US-11643657-B2 | Chiral control | WAVE LIFE SCIENCES LTD. (SG) | 2023-05-09 | — | — | US | disclosed |
| US-20170275621-A1 | CHIRAL CONTROL | WAVE LIFE SCIENCES USA, INC. | 2017-09-28 | — | — | US | disclosed |
| US-20150211006-A1 | CHIRAL CONTROL | WAVE LIFE SCIENCES USA, INC. | 2015-07-30 | — | — | US | disclosed |
| US-20150211006-A1 | CHIRAL CONTROL | WAVE LIFE SCIENCES USA, INC. | 2015-07-30 | — | — | US | disclosed |
| WO-2014012081-A2 | CHIRAL CONTROL | ONTORII, INC. (US) | 2014-01-16 | — | — | WO | disclosed |
| WO-1995004740-A1 | 7α-AMINO-1,1-DIOXOCEFEM L-VALYLAMIDES | DOMPE' S.P.A. (IT) | 1995-02-16 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170275621-A1 | CHIRAL CONTROL | RNGTT, POLI, NSUN3 | PIN1 246/4885KMT2A 2211/4885CASP3 3639/4885 |
| US-20240229026-A1 | CHIRAL CONTROL | RNGTT, POLI, NSUN3 | PIN1 246/4885KMT2A 2211/4885CASP3 3639/4885 |
| US-20150211006-A1 | CHIRAL CONTROL | RNGTT, POLI, NSUN3 | PIN1 246/4885KMT2A 2211/4885CASP3 3639/4885 |
| US-11643657-B2 | Chiral control | RNGTT, POLI, NSUN3 | PIN1 246/4885KMT2A 2211/4885CASP3 3639/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.