SCHEMBL927042

SCHEMBL927042

COc1cc2ccsc2c2ncsc12

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 1/20 0.41
TSHR P16473 1/20 0.41
PDGFRB P09619 4/20 0.39
PDGFRA P16234 4/20 0.39
SRC P12931 1/20 0.34
NPC1 O15118 1/20 0.34
RAB9A P51151 1/20 0.34
ALDH1A1 P00352 3/20 0.33
RPS6KB2 Q9UBS0 2/20 0.33
SMPD3 Q9NY59 1/20 0.33
PDE10A Q9Y233 1/20 0.33
KARS1 Q15046 1/20 0.32
KEAP1 Q14145 1/20 0.32
ECE1 P42892 1/20 0.31
MKNK1 Q9BUB5 1/20 0.31
HTR2A P28223 1/20 0.31
HTR2C P28335 1/20 0.31
MEN1 O00255 1/20 0.31
PKM P14618 1/20 0.31
KMT2A Q03164 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18459024 0.77 ALDH1A1 (0.48) MAPTTSHRNPC1ALDH1A1KARS1
SCHEMBL4803345 0.74 MAPT (0.40) MAPTTSHRPDGFRBPDGFRANPC1
SCHEMBL15018567 0.74 ACHE (0.43) MAPTTSHRPDGFRBPDGFRASRC
SCHEMBL10368828 0.74 CA12 (0.42) MAPTTSHRALDH1A1MEN1KMT2A
SCHEMBL14673728 0.73 MAPT (0.41) MAPTTSHRPDGFRBPDGFRANPC1
SCHEMBL18416896 0.73 ALDH1A1 (0.41) MAPTTSHRPDGFRBPDGFRANPC1
SCHEMBL12804731 0.71 ALDH1A1 (0.40) MAPTTSHRPDGFRBPDGFRANPC1
SCHEMBL16009860 0.70 MAOA (0.42) MAPTTSHRNPC1ALDH1A1KEAP1
SCHEMBL10907897 0.70 TSHR (0.61) MAPTTSHRNPC1RAB9AALDH1A1
SCHEMBL10725852 0.69 PDGFRB (0.39) MAPTTSHRPDGFRBPDGFRASRC

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 331 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1859954-B2 Planographic printing plate precursor and stack thereof FUJIFILM CORP (JP) 2017-11-08 EP disclosed
EP-2006738-B1 Lithographic printing plate precursor FUJIFILM CORP (JP) 2017-09-06 EP disclosed
EP-1975707-B1 Curable composition and planographic printing plate precursor FUJIFILM CORP (JP) 2017-07-19 EP disclosed
EP-2259141-B1 PROCESS FOR PRODUCING LITHOGRAPHIC PRINTING PLATE FUJIFILM CORP (JP) 2016-11-23 EP disclosed
EP-1939687-B1 Polymerizable composition and lithographic printing plate precursor FUJIFILM CORP (JP) 2016-09-14 EP disclosed
EP-1564591-B1 Polymerizable composition FUJIFILM CORP (JP) 2016-08-03 EP disclosed
EP-2503393-B2 Method for preparation of lithographic printing plate FUJIFILM CORP (JP) 2016-07-20 EP disclosed
EP-2042312-B1 Processing method of lithographic printing plate precursor FUJIFILM CORP (JP) 2016-05-18 EP disclosed
EP-3021167-A1 LITHOGRAPHIC PRINTING PLATE PRECURSOR AND METHOD OF PREPARING LITHOGRAPHIC PRINTING PLATE Fujifilm Corporation (JP) 2016-05-18 EP disclosed
EP-2131239-B1 Processing liquid for lithographic printing plate development and method of producing lithographic printing plates FUJIFILM CORP (JP) 2016-03-23 EP disclosed
US-4075017-A Photothermographic material containing a combination of energy-sensitive organic dyes and process of forming a positive or negative image with the material EASTMAN KODAK COMPANY (US) 1978-02-21 US disclosed
US-4030932-A PHOTOGRAPHY EASTMAN KODAK COMPANY (US) 1977-06-21 US disclosed
US-4026884-A SPECTRAL SENSITIZERS FOR SILVER HALIDE EMULSIONS EASTMAN KODAK COMPANY (US) 1977-05-31 US disclosed
US-4025349-A Silver halide photographic elements spectrally sensitized with an acetylenic analog of cyanine or merocyanine dyes EASTMAN KODAK COMPANY (US) 1977-05-24 US disclosed
US-RE29168-E HEAT SENSITIVE, ANTIHALATION LAYER EASTMAN KODAK COMPANY (US) 1977-04-05 US disclosed
US-4007170-A SILVER HALIDE SENSITIZERS EASTMAN KODAK COMPANY (US) 1977-02-08 US disclosed
US-4003750-A METHINE DYES EASTMAN KODAK COMPANY (US) 1977-01-18 US disclosed
US-3996215-A PHOTOGRAPHIC FILTER OR ANTIHALATION DYES FUJI PHOTO FILM CO., LTD. (JA) 1976-12-07 US disclosed
US-3943142-A Dye intermediates and their preparation and use in the synthesis of methine dyes EASTMAN KODAK COMPANY (US) 1976-03-09 US disclosed
US-3936308-A Photographic emulsions containing methine dyes having a 1H-imidazo[4,5-b]pyrazine nucleus EASTMAN KODAK COMPANY (US) 1976-02-03 US disclosed