SCHEMBL927153

SCHEMBL927153

NCc1cccc(OCCC(=O)O)c1

nearest known ligand 0.53

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
FFAR1 O14842 6/20 0.53
CFD P00746 1/20 0.51
L3MBTL1 Q9Y468 2/20 0.47
TSHR P16473 3/20 0.47
MAPK1 P28482 1/20 0.46
TDP1 Q9NUW8 1/20 0.46
RECQL P46063 1/20 0.45
FFAR4 Q5NUL3 1/20 0.45
PLA2G4B P0C869 1/20 0.44
LOXL2 Q9Y4K0 1/20 0.44
MCL1 Q07820 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24675655 0.91 FFAR1 (0.49) FFAR1CFDL3MBTL1TSHRMAPK1
SCHEMBL24675865 0.91 FFAR1 (0.49) FFAR1CFDL3MBTL1TSHRMAPK1
SCHEMBL24675243 0.87 PLA2G4B (0.46) FFAR1CFDL3MBTL1MAPK1PLA2G4B
Hydrochloric Acid SCHEMBL25290504 0.86 PLA2G4B (0.46) FFAR1CFDL3MBTL1MAPK1PLA2G4B
SCHEMBL24675498 0.84 CNR1 (0.47) FFAR1CFDFFAR4PLA2G4B
Hydrochloric Acid SCHEMBL27225814 0.83 CNR1 (0.47) FFAR1CFDFFAR4PLA2G4B
SCHEMBL2936246 0.83 PPARA (0.60) FFAR1CFDMAPK1
SCHEMBL29403718 0.83 PPARA (0.60) FFAR1CFDMAPK1
SCHEMBL928209 0.83 L3MBTL1 (0.62) FFAR1L3MBTL1TSHRFFAR4
Hydrochloric Acid SCHEMBL4933711 0.82 PPARA (0.58) FFAR1CFDMAPK1LOXL2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-102746214-A Novel indoline compounds FOURNIER LAB SA 2012-10-24 CN disclosed
US-7872021-B2 LXR receptor modulators LABORATORIES FOURNIER S.A. (FR) 2011-01-18 US disclosed
US-7465811-B2 Indoline compounds LABORATOIRES FOURNIER S.A. (FR) 2008-12-16 US disclosed
US-20080119465-A1 Novel Indoline Compounds LABORATORIES FOURNIER S.A. (FR) 2008-05-22 US disclosed
US-20070099960-A1 LXR receptor modulators LABORATOIRES FOURNIER S.A. (FR) 2007-05-03 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070099960-A1 LXR receptor modulators NR1H2, NR1H3, PPARD FFAR1 40/4885CFD 3907/4885L3MBTL1 3947/4885
US-20080119465-A1 Novel Indoline Compounds GPR119, INSR, IRS1 FFAR1 55/4885CFD 3963/4885L3MBTL1 1493/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.