Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | COL1A1 | P02452 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.36 |
| ▸ | UBE2M | P61081 | 4/20 | 0.36 |
| ▸ | DCUN1D1 | Q96GG9 | 4/20 | 0.36 |
| ▸ | MEN1 | O00255 | 3/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | PTBP1 | P26599 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9271674 | 1.00 | COL1A1 (0.38) | COL1A1ALDH1A1KMT2AUBE2MDCUN1D1 | |
| SCHEMBL9273333 | 0.90 | CYP3A4 (0.41) | ALDH1A1KMT2AUBE2MDCUN1D1MEN1 | |
| SCHEMBL9273330 | 0.90 | CYP3A4 (0.41) | ALDH1A1KMT2AUBE2MDCUN1D1MEN1 | |
| SCHEMBL9272129 | 0.87 | UBE2M (0.46) | COL1A1UBE2MDCUN1D1 | |
| SCHEMBL9272134 | 0.87 | UBE2M (0.46) | COL1A1UBE2MDCUN1D1 | |
| SCHEMBL9269480 | 0.77 | CYP3A4 (0.44) | ALDH1A1UBE2MDCUN1D1LMNAPTBP1 | |
| SCHEMBL9269474 | 0.77 | CYP3A4 (0.44) | ALDH1A1UBE2MDCUN1D1LMNAPTBP1 | |
| SCHEMBL9269777 | 0.71 | ALDH1A1 (0.47) | ALDH1A1KMT2AUBE2MDCUN1D1MEN1 | |
| SCHEMBL9269779 | 0.71 | ALDH1A1 (0.47) | ALDH1A1KMT2AUBE2MDCUN1D1MEN1 | |
| SCHEMBL9273248 | 0.70 | EPHX1 (0.42) | ALDH1A1KMT2ADCUN1D1MEN1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5420164-A | Enzyme inhibitors | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1995-05-30 | — | — | US | disclosed |