Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLAT | P00750 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 2/20 | 0.37 |
| ▸ | CHUK | O15111 | 1/20 | 0.37 |
| ▸ | TXNRD1 | Q16881 | 1/20 | 0.37 |
| ▸ | NOX4 | Q9NPH5 | 1/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | S1PR1 | P21453 | 4/20 | 0.36 |
| ▸ | S1PR3 | Q99500 | 3/20 | 0.36 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.36 |
| ▸ | FEN1 | P39748 | 1/20 | 0.36 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | ABCC8 | Q09428 | 1/20 | 0.34 |
| ▸ | KCNJ11 | Q14654 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30646382 | 0.86 | MPL (0.46) | PLATL3MBTL1POLBCHUKTXNRD1 | |
| SCHEMBL30646372 | 0.86 | TRPA1 (0.39) | S1PR1S1PR3AKR1B1CYP1A2CYP2D6 | |
| SCHEMBL30646377 | 0.84 | L3MBTL1 (0.43) | PLATL3MBTL1POLBCHUKTXNRD1 | |
| SCHEMBL30646393 | 0.84 | POLB (0.37) | L3MBTL1POLBCHUKTXNRD1NOX4 | |
| SCHEMBL30646380 | 0.84 | L3MBTL1 (0.39) | L3MBTL1POLBCHUKTXNRD1NOX4 | |
| SCHEMBL30646390 | 0.82 | GAA (0.44) | TXNRD1MAPTMAPK1NPC1RAB9A | |
| SCHEMBL29111913 | 0.81 | SPHK2 (0.41) | PLATL3MBTL1POLBMAPTMAPK1 | |
| SCHEMBL9272000 | 0.77 | LMNA (0.55) | CHUKTXNRD1NOX4MAPTS1PR1 | |
| SCHEMBL29111939 | 0.76 | IDH2 (0.40) | PLATPOLBCHUKTXNRD1NOX4 | |
| SCHEMBL29111900 | 0.75 | DGAT2 (0.48) | MAPTAKR1B1GAALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116874441-A | Flexible aryl formamide derivative containing 1,2, 4-oxadiazole as well as preparation method and application thereof | 贵州大学 | 2023-10-13 | — | — | CN | disclosed |