Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.58 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.54 |
| ▸ | POLB | P06746 | 3/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.54 |
| ▸ | MEN1 | O00255 | 4/20 | 0.54 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.53 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
| ▸ | ATM | Q13315 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | CCR1 | P32246 | 1/20 | 0.48 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.48 |
| ▸ | USP2 | O75604 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9273198 | 0.83 | NPC1 (0.65) | MAPTALDH1A1LMNAKMT2AMEN1 | |
| SCHEMBL21230467 | 0.79 | TAS1R3 (0.71) | MAPTSIGMAR1ALDH1A1POLBKDM4E | |
| SCHEMBL9275859 | 0.77 | RAB9A (0.62) | MAPTALDH1A1POLBLMNAKMT2A | |
| SCHEMBL20671206 | 0.75 | HTT (0.64) | MAPTSIGMAR1ALDH1A1POLBKDM4E | |
| SCHEMBL9274428 | 0.75 | KMT2A (0.62) | ALDH1A1KDM4EKMT2AMEN1TAS1R3 | |
| SCHEMBL9270646 | 0.74 | RAB9A (0.67) | MAPTALDH1A1KDM4ELMNAKMT2A | |
| SCHEMBL9270866 | 0.73 | NPC1 (0.62) | ALDH1A1POLBLMNAKMT2AMEN1 | |
| SCHEMBL10537786 | 0.72 | MAPT (0.67) | MAPTSIGMAR1ALDH1A1POLBKDM4E | |
| SCHEMBL9271464 | 0.71 | NPC1 (0.59) | ALDH1A1KMT2AMEN1 | |
| SCHEMBL9273027 | 0.70 | EPHX2 (0.51) | ALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5420164-A | Enzyme inhibitors | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1995-05-30 | — | — | US | disclosed |
| EP-0507291-A1 | Cyclohexylurea compounds | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1992-10-07 | — | — | EP | disclosed |