Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.49 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.49 |
| ▸ | PRNP | P04156 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 3/20 | 0.43 |
| ▸ | LMNA | P02545 | 4/20 | 0.42 |
| ▸ | PPARG | P37231 | 3/20 | 0.42 |
| ▸ | NCOA2 | Q15596 | 3/20 | 0.42 |
| ▸ | NCOA1 | Q15788 | 3/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9201879 | 0.77 | KDM4E (0.42) | KDM4EALDH1A1RXFP1PRNPHPGD | |
| SCHEMBL9202376 | 0.76 | KDM4E (0.41) | KDM4EALDH1A1RXFP1PRNPHPGD | |
| SCHEMBL9202386 | 0.75 | TP53 (0.51) | KDM4EALDH1A1HPGDGAAKMT2A | |
| SCHEMBL9712333 | 0.75 | ALDH1A1 (0.49) | KDM4EALDH1A1RXFP1LMNAMAPT | |
| SCHEMBL9197584 | 0.74 | ALDH1A1 (0.47) | KDM4EALDH1A1RXFP1KMT2AMEN1 | |
| SCHEMBL15154503 | 0.71 | MEN1 (0.59) | KDM4EALDH1A1HPGDLMNAMAPT | |
| SCHEMBL9202310 | 0.70 | MEN1 (0.71) | KDM4EALDH1A1RXFP1PRNPLMNA | |
| SCHEMBL7612454 | 0.70 | MEN1 (0.52) | KDM4EALDH1A1HPGDMAPTNPSR1 | |
| SCHEMBL9712252 | 0.70 | ALDH1A1 (0.41) | KDM4EALDH1A1RXFP1PRNPHPGD | |
| SCHEMBL9712318 | 0.70 | ALDH1A1 (0.42) | KDM4EALDH1A1RXFP1PRNPHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0639182-A1 | QUINOLINE DERIVATIVES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1995-02-22 | — | — | EP | disclosed |
| WO-1992018483-A1 | QUINOLINE DERIVATIVES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1992-10-29 | — | — | WO | disclosed |