Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.40 |
| ▸ | PRNP | P04156 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.38 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.37 |
| ▸ | KDR | P35968 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | CCR6 | P51684 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9275276 | 0.77 | PDGFRB (0.52) | ALDH1A1KMT2ASMN1; SMN2LMNARXFP1 | |
| SCHEMBL9202120 | 0.76 | KMT2A (0.41) | ALDH1A1KMT2ASMN1; SMN2LMNARXFP1 | |
| SCHEMBL9273136 | 0.75 | SMN1; SMN2 (0.48) | ALDH1A1KMT2ASMN1; SMN2LMNARXFP1 | |
| SCHEMBL9287808 | 0.72 | PDGFRB (0.43) | ALDH1A1KMT2ASMN1; SMN2LMNARXFP1 | |
| SCHEMBL9283825 | 0.71 | LMNA (0.43) | ALDH1A1KMT2ASMN1; SMN2LMNARXFP1 | |
| SCHEMBL9712333 | 0.70 | ALDH1A1 (0.49) | ALDH1A1KMT2ASMN1; SMN2LMNARXFP1 | |
| SCHEMBL9273290 | 0.70 | KDM4E (0.49) | ALDH1A1KMT2ASMN1; SMN2LMNARXFP1 | |
| SCHEMBL9202123 | 0.69 | KMT2A (0.39) | ALDH1A1KMT2ASMN1; SMN2LMNARXFP1 | |
| SCHEMBL9197584 | 0.69 | ALDH1A1 (0.47) | ALDH1A1KMT2ARXFP1KDM4EMEN1 | |
| SCHEMBL9712252 | 0.68 | ALDH1A1 (0.41) | ALDH1A1KMT2ASMN1; SMN2LMNARXFP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1992018483-A1 | QUINOLINE DERIVATIVES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1992-10-29 | — | — | WO | disclosed |