Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX7 | Q99572 | 11/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | NR1I3 | Q14994 | 5/20 | 0.42 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.39 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9264401 | 0.89 | ENPP2 (0.46) | P2RX7TRPA1SIGMAR1KDM4ENPC1 | |
| SCHEMBL9279945 | 0.86 | KMT2A (0.43) | P2RX7TRPA1SIGMAR1KDM4ENPC1 | |
| SCHEMBL9259178 | 0.84 | P2RX7 (0.42) | P2RX7TDP1TRPA1SIGMAR1 | |
| SCHEMBL9284417 | 0.79 | NPC1 (0.41) | P2RX7KDM4ENPC1RAB9ASMN1; SMN2 | |
| SCHEMBL9260174 | 0.77 | ALDH1A1 (0.41) | KDM4ENPC1RAB9ASMN1; SMN2 | |
| SCHEMBL9262714 | 0.76 | RAB9A (0.40) | KDM4ENPC1RAB9ASMN1; SMN2 | |
| SCHEMBL9262401 | 0.76 | NPC1 (0.39) | KDM4ENPC1RAB9ASMN1; SMN2 | |
| SCHEMBL6356874 | 0.76 | P2RX7 (0.64) | P2RX7TRPA1SIGMAR1NPC1RAB9A | |
| SCHEMBL9261855 | 0.75 | MAPT (0.43) | KDM4ENPC1RAB9ASMN1; SMN2 | |
| SCHEMBL9262577 | 0.74 | ALDH1A1 (0.39) | KDM4ENPC1RAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0641340-A1 | NEW 3-(SUBSTITUTED TETRAZOLYL)-4-OXO-4H-PYRIDO- 1,2-a]PYRIMIDINES, SALTS THEREOF, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM AND PROCESS FOR PREPARING SAME | CHINOIN Gyogyszer és Vegyészeti Termékek Gyára RT. (HU) | 1995-03-08 | — | — | EP | disclosed |
| WO-1993004065-A1 | NEW 3-(SUBSTITUTED TETRAZOLYL)-4-OXO-4H-PYRIDO-[1,2-a]PYRIMIDINES, SALTS THEREOF, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM AND PROCESS FOR PREPARING SAME | CHINOIN GYÓGYSZER- ÉS VEGYÉSZETI TERMÉKEK GYÁRA RT. (HU) | 1993-03-04 | — | — | WO | disclosed |