Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 13/20 | 0.42 |
| ▸ | PPARA | Q07869 | 13/20 | 0.42 |
| ▸ | ALOX5 | P09917 | 11/20 | 0.42 |
| ▸ | PTGES | O14684 | 8/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10789684 | 0.86 | LTA4H (0.44) | PPARGPPARAALOX5PTGES | |
| SCHEMBL9856294 | 0.83 | PPARG (0.39) | PPARGPPARAALOX5PTGESTDP1 | |
| SCHEMBL9856269 | 0.83 | TAAR1 (0.44) | PPARGPPARAALOX5PTGESTDP1 | |
| SCHEMBL9268024 | 0.83 | NR1I2 (0.49) | PPARGPPARAALOX5PTGES | |
| SCHEMBL9275804 | 0.80 | LMNA (0.36) | PPARGPPARAALOX5PTGESTDP1 | |
| SCHEMBL9262825 | 0.78 | NPC1 (0.40) | PPARGPPARAALOX5PTGES | |
| SCHEMBL23295252 | 0.78 | NQO1 (0.34) | PPARGPPARAALOX5PTGES | |
| SCHEMBL9856427 | 0.77 | PPARG (0.38) | PPARGPPARAALOX5PTGES | |
| SCHEMBL9856170 | 0.77 | CA12 (0.44) | — | |
| SCHEMBL9274915 | 0.77 | LMNA (0.53) | PPARGPPARAALOX5PTGESTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5389651-A | Nitrogen-containing heterocyclyl-oxy and -thio compounds useful as pesticides | SANDOZ LTD. (CH) | 1995-02-14 | — | — | US | disclosed |