Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 1/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.41 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9275586 | 0.89 | HTR1A (0.40) | HPGDUSP2 | |
| SCHEMBL9277120 | 0.87 | CHRM2 (0.39) | USP2ALOX15 | |
| SCHEMBL9275199 | 0.87 | OPRK1 (0.36) | SLC6A4SLC6A3OPRK1 | |
| SCHEMBL9279274 | 0.87 | ACACB (0.37) | SLC6A4SLC6A3OPRK1 | |
| SCHEMBL9100563 | 0.86 | SLC6A4 (0.41) | SLC6A4SLC6A3 | |
| SCHEMBL9100555 | 0.86 | SLC6A4 (0.41) | SLC6A4SLC6A3 | |
| SCHEMBL9280325 | 0.86 | USP2 (0.50) | USP2ALOX15 | |
| SCHEMBL9280528 | 0.84 | HDAC8 (0.47) | OPRK1 | |
| SCHEMBL9276710 | 0.84 | SLC6A4 (0.43) | SLC6A4SLC6A3 | |
| SCHEMBL9102588 | 0.84 | SLC6A4 (0.43) | SLC6A4SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012074469-A1 | NEW IKACH BLOCKERS | ASTRAZENECA AB (SE) | 2012-06-07 | — | — | WO | disclosed |