Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRK1 | P41145 | 1/20 | 0.36 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.35 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.35 |
| ▸ | TAS1R2 | Q8TE23 | 1/20 | 0.35 |
| ▸ | MAOA | P21397 | 1/20 | 0.35 |
| ▸ | MAOB | P27338 | 1/20 | 0.35 |
| ▸ | DPP4 | P27487 | 1/20 | 0.35 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.35 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.35 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.35 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.35 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.35 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9287812 | 0.88 | HTR7 (0.38) | MAOAMAOBKCNH2GRIN2BHTR1A | |
| SCHEMBL9280185 | 0.88 | P2RX7 (0.38) | TSHR | |
| SCHEMBL31478879 | 0.87 | MAOA (0.38) | OPRK1TAS1R3TAS1R1TAS1R2MAOA | |
| SCHEMBL9101316 | 0.87 | MAOA (0.38) | OPRK1TAS1R3TAS1R1TAS1R2MAOA | |
| SCHEMBL9101325 | 0.87 | MAOA (0.38) | OPRK1TAS1R3TAS1R1TAS1R2MAOA | |
| SCHEMBL9274754 | 0.87 | SLC6A4 (0.41) | OPRK1SLC6A4SLC6A3 | |
| SCHEMBL9277511 | 0.85 | HDAC8 (0.45) | TAS1R3TAS1R1TAS1R2KCNH2GPBAR1 | |
| SCHEMBL9279274 | 0.83 | ACACB (0.37) | OPRK1TAS1R3TAS1R1TAS1R2KCNH2 | |
| SCHEMBL9275011 | 0.81 | ALDH1A1 (0.36) | DPP4DPP7SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL9275586 | 0.81 | HTR1A (0.40) | CYP2D6TSHRHTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012074469-A1 | NEW IKACH BLOCKERS | ASTRAZENECA AB (SE) | 2012-06-07 | — | — | WO | disclosed |