Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | UBE2M | P61081 | 13/20 | 0.49 |
| ▸ | DCUN1D1 | Q96GG9 | 13/20 | 0.49 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.45 |
| ▸ | THRB | P10828 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | USP2 | O75604 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | CASP1 | P29466 | 1/20 | 0.43 |
| ▸ | CASP7 | P55210 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9273627 | 0.89 | THRB (0.54) | UBE2MDCUN1D1THRBLMNAUSP2 | |
| SCHEMBL9273625 | 0.89 | THRB (0.54) | UBE2MDCUN1D1THRBLMNAUSP2 | |
| SCHEMBL9266858 | 0.83 | ALDH1A1 (0.40) | THRBLMNAUSP2ALDH1A1KDM4E | |
| SCHEMBL9266860 | 0.83 | ALDH1A1 (0.40) | THRBLMNAUSP2ALDH1A1KDM4E | |
| SCHEMBL9257513 | 0.82 | THRB (0.50) | UBE2MDCUN1D1ROCK2THRBLMNA | |
| SCHEMBL9274697 | 0.82 | UBE2M (0.50) | UBE2MDCUN1D1THRBLMNAUSP2 | |
| SCHEMBL9274690 | 0.82 | UBE2M (0.50) | UBE2MDCUN1D1THRBLMNAUSP2 | |
| SCHEMBL9273323 | 0.81 | DCUN1D1 (0.48) | UBE2MDCUN1D1THRB | |
| SCHEMBL9273319 | 0.81 | DCUN1D1 (0.48) | UBE2MDCUN1D1THRB | |
| SCHEMBL9271572 | 0.80 | DCUN1D1 (0.50) | UBE2MDCUN1D1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5420164-A | Enzyme inhibitors | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1995-05-30 | — | — | US | claimed |
| EP-0507291-A1 | Cyclohexylurea compounds | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1992-10-07 | — | — | EP | claimed |
| US-5420164-A | Enzyme inhibitors | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1995-05-30 | — | — | US | disclosed |
| EP-0507291-A1 | Cyclohexylurea compounds | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1992-10-07 | — | — | EP | disclosed |