Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 2/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.53 |
| ▸ | LMNA | P02545 | 2/20 | 0.52 |
| ▸ | USP2 | O75604 | 1/20 | 0.52 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.52 |
| ▸ | UBE2M | P61081 | 4/20 | 0.51 |
| ▸ | DCUN1D1 | Q96GG9 | 4/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9273627 | 1.00 | THRB (0.54) | THRBALDH1A1LMNAUSP2NPSR1 | |
| SCHEMBL9275183 | 0.89 | UBE2M (0.49) | THRBALDH1A1LMNAUSP2NPSR1 | |
| SCHEMBL9265659 | 0.87 | ALDH1A1 (0.56) | THRBALDH1A1LMNAUSP2NPSR1 | |
| SCHEMBL9265663 | 0.87 | ALDH1A1 (0.56) | THRBALDH1A1LMNAUSP2NPSR1 | |
| SCHEMBL19555604 | 0.84 | PPARG (0.51) | ALDH1A1LMNAUSP2NPSR1UBE2M | |
| SCHEMBL19555602 | 0.84 | PPARG (0.51) | ALDH1A1LMNAUSP2NPSR1UBE2M | |
| SCHEMBL19555609 | 0.82 | UBE2M (0.57) | ALDH1A1UBE2MDCUN1D1MEN1KMT2A | |
| SCHEMBL19555610 | 0.82 | UBE2M (0.57) | ALDH1A1UBE2MDCUN1D1MEN1KMT2A | |
| SCHEMBL18657684 | 0.81 | UBE2M (0.79) | UBE2MDCUN1D1 | |
| SCHEMBL9270461 | 0.80 | ALDH1A1 (0.55) | THRBALDH1A1LMNAUSP2NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5420164-A | Enzyme inhibitors | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1995-05-30 | — | — | US | disclosed |