Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 10/20 | 0.45 |
| ▸ | OPRL1 | P41146 | 10/20 | 0.45 |
| ▸ | OPRD1 | P41143 | 9/20 | 0.45 |
| ▸ | OPRK1 | P41145 | 9/20 | 0.45 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | DRD4 | P21917 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | DRD2 | P14416 | 1/20 | 0.39 |
| ▸ | DRD1 | P21728 | 1/20 | 0.39 |
| ▸ | DRD5 | P21918 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17888234 | 0.84 | OPRM1 (0.62) | OPRM1OPRL1OPRD1OPRK1MAPK1 | |
| SCHEMBL2079404 | 0.82 | ALOX15 (0.41) | OPRM1OPRL1OPRD1OPRK1SMN1; SMN2 | |
| SCHEMBL83658 | 0.82 | OPRL1 (0.42) | OPRM1OPRL1OPRD1OPRK1 | |
| SCHEMBL1703171 | 0.79 | ALOX15 (0.38) | OPRM1OPRL1OPRD1OPRK1SMN1; SMN2 | |
| SCHEMBL7102084 | 0.79 | ALOX15 (0.38) | OPRM1OPRL1OPRD1OPRK1SMN1; SMN2 | |
| SCHEMBL29710660 | 0.79 | ALOX15 (0.38) | OPRM1OPRL1OPRD1OPRK1SMN1; SMN2 | |
| SCHEMBL16565590 | 0.79 | OPRL1 (0.51) | OPRM1OPRL1OPRD1OPRK1MAPK1 | |
| SCHEMBL8049532 | 0.79 | OPRM1 (0.60) | OPRM1OPRL1OPRD1OPRK1MAPK1 | |
| SCHEMBL632646 | 0.77 | OPRM1 (0.37) | OPRM1OPRL1OPRD1OPRK1SMN1; SMN2 | |
| SCHEMBL7101793 | 0.77 | OPRM1 (0.37) | OPRM1OPRL1OPRD1OPRK1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8129534-B2 | Chemical compounds | SYNGENTA CROP PROTECTION, INC. (US) | 2012-03-06 | — | — | US | disclosed |
| US-4558049-A | Antipsycotic benzoxazines | FARMITALIA CARLO ERBA S.P.A. (IT) | 1985-12-10 | — | — | US | disclosed |