Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRL1 | P41146 | 20/20 | 0.42 |
| ▸ | OPRM1 | P35372 | 18/20 | 0.42 |
| ▸ | OPRD1 | P41143 | 18/20 | 0.42 |
| ▸ | OPRK1 | P41145 | 18/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2079404 | 0.82 | ALOX15 (0.41) | OPRL1OPRM1OPRD1OPRK1 | |
| SCHEMBL16777011 | 0.82 | OPRM1 (0.60) | OPRL1OPRM1OPRD1OPRK1 | |
| SCHEMBL92778 | 0.82 | OPRM1 (0.45) | OPRL1OPRM1OPRD1OPRK1 | |
| SCHEMBL29710660 | 0.79 | ALOX15 (0.38) | OPRL1OPRM1OPRD1OPRK1 | |
| SCHEMBL1703171 | 0.79 | ALOX15 (0.38) | OPRL1OPRM1OPRD1OPRK1 | |
| SCHEMBL7102084 | 0.79 | ALOX15 (0.38) | OPRL1OPRM1OPRD1OPRK1 | |
| SCHEMBL632646 | 0.77 | OPRM1 (0.37) | OPRL1OPRM1OPRD1OPRK1 | |
| SCHEMBL7101793 | 0.77 | OPRM1 (0.37) | OPRL1OPRM1OPRD1OPRK1 | |
| SCHEMBL10916463 | 0.76 | OPRL1 (0.70) | OPRL1 | |
| SCHEMBL8222575 | 0.74 | SIGMAR1 (0.57) | OPRL1OPRM1OPRD1OPRK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9045422-B2 | Piperidine derivatives with pesticidal properties | SYNGENTA PARTICIPATIONS AG (CH) | 2015-06-02 | — | — | US | disclosed |
| US-20130310399-A1 | CHEMICAL COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2013-11-21 | — | — | US | disclosed |
| US-8546569-B2 | Chemical compounds | SYNGENTA CROP PROTECTION, INC. (US) | 2013-10-01 | — | — | US | disclosed |
| US-8546569-B2 | Chemical compounds | SYNGENTA CROP PROTECTION, INC. (US) | 2013-10-01 | — | — | US | disclosed |
| US-20120270885-A1 | CHEMICAL COMPOUNDS | SYNGENTA CROP PROTECTION LLC (US) | 2012-10-25 | — | — | US | disclosed |
| US-8129534-B2 | Chemical compounds | SYNGENTA CROP PROTECTION, INC. (US) | 2012-03-06 | — | — | US | disclosed |
| US-20090042938-A1 | Chemical Compounds | SYNGENTA CROP PROTECTION, INC. (US) | 2009-02-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120270885-A1 | CHEMICAL COMPOUNDS | H1-0, CHRM1, MRM1 | OPRL1 1165/4885OPRM1 28/4885OPRD1 298/4885 |
| US-20090042938-A1 | Chemical Compounds | CHRM1, MRM1, H1-0 | OPRL1 1200/4885OPRM1 24/4885OPRD1 295/4885 |
| US-20130310399-A1 | CHEMICAL COMPOUNDS | ACHE, CHRM1, CHRM2 | OPRL1 1743/4885OPRM1 33/4885OPRD1 317/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.