Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 3/20 | 0.49 |
| ▸ | LMNA | P02545 | 3/20 | 0.49 |
| ▸ | POLB | P06746 | 3/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | AHR | P35869 | 1/20 | 0.49 |
| ▸ | CASP6 | P55212 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | NPBWR1 | P48145 | 1/20 | 0.44 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.44 |
| ▸ | PPARG | P37231 | 1/20 | 0.42 |
| ▸ | PPARA | Q07869 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9278755 | 0.99 | LMNA (0.48) | RAB9ALMNAPOLBTDP1MEN1 | |
| SCHEMBL2329463 | 0.91 | RAB9A (0.44) | RAB9ALMNAPOLBTDP1MEN1 | |
| SCHEMBL9287251 | 0.91 | RAB9A (0.51) | RAB9ALMNAPOLBTDP1MEN1 | |
| SCHEMBL2323834 | 0.91 | RAB9A (0.44) | RAB9ALMNAPOLBTDP1MEN1 | |
| SCHEMBL9285226 | 0.90 | LTB4R (0.52) | RAB9ALMNAPOLBTDP1MEN1 | |
| SCHEMBL2326535 | 0.90 | LTB4R (0.52) | RAB9ALMNAPOLBTDP1MEN1 | |
| SCHEMBL2328156 | 0.90 | MAPT (0.48) | RAB9ALMNAPOLBTDP1MEN1 | |
| SCHEMBL2330131 | 0.89 | ALDH1A1 (0.45) | RAB9ALMNAPOLBTDP1MEN1 | |
| SCHEMBL9281733 | 0.88 | PDE3B (0.47) | LTB4RPPARGPPARACYP1A2PDE2A | |
| SCHEMBL2323904 | 0.87 | PPARA (0.48) | LTB4RPPARGPPARACYP1A2PDE2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1995007263-A1 | 1,2-DI(HETERO)ARYLBENZIMIDAZOLE DERIVATIVES, THEIR PREPARATION AND THEIR USE AS PROSTACYCLIN (PGI2) MIMETICS | SCHERING AKTIENGESELLSCHAFT (DE) | 1995-03-16 | — | — | WO | disclosed |